1044277-01-1

Basic information

• Product Name: (S)-4-(3-fluorophenyl)-7-((4-(1,1,1-trifluoro-2-hydroxybutan-2-yl)-1H-1,2,3-triazol-1-yl)methyl)-2H-chromen-2-one
• Synonyms: (S)-4-(3-fluorophenyl)-7-({4-[1-hydroxy-1-(trifluoromethyl)propyl]-1H-1,2,3-triazol-1-yl}methyl)-2H-chromen-2-one
• CAS NO: 1044277-01-1
• Molecular Formula: C22H17F4N3O3
• Molecular Weight: 447.389
• Mol File: 1044277-01-1.mol

Chemical Properties

• CAS DataBase Reference: (S)-4-(3-fluorophenyl)-7-((4-(1,1,1-trifluoro-2-hydroxybutan-2-yl)-1H-1,2,3-triazol-1-yl)methyl)-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-(3-fluorophenyl)-7-((4-(1,1,1-trifluoro-2-hydroxybutan-2-yl)-1H-1,2,3-triazol-1-yl)methyl)-2H-chromen-2-one(1044277-01-1)
• EPA Substance Registry System: (S)-4-(3-fluorophenyl)-7-((4-(1,1,1-trifluoro-2-hydroxybutan-2-yl)-1H-1,2,3-triazol-1-yl)methyl)-2H-chromen-2-one(1044277-01-1)

Safety Data

• Hazardous Substances Data: 1044277-01-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(S)-4-(3-fluorophenyl)-7-((4-(1,1,1-trifluoro-2-hydroxybutan-2-yl)-1H-1,2,3-triazol-1-yl)methyl)-2H-chromen-2-one is used as a potential drug candidate for the development of new medications. Its complex chemical structure suggests that it may have biological activities related to the inhibition of certain enzymes or receptors, which could be beneficial in treating various medical conditions.
Used in Research and Development:
In the field of research and development, (S)-4-(3-fluorophenyl)-7-((4-(1,1,1-trifluoro-2-hydroxybutan-2-yl)-1H-1,2,3-triazol-1-yl)methyl)-2H-chromen-2-one serves as a valuable compound for further study. Its potential pharmaceutical properties make it an interesting subject for scientists to explore its pharmacological properties and possible therapeutic applications. Further research is necessary to fully understand its capabilities and maximize its potential in the medical field.

Upstream product

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• 1044277-03-3 1-ethyl-1-(trifluoromethyl)prop-2-yn-1-yl 4-nitrobenzoate 
• 1044277-10-2 1-ethyl-1-(trifluoromethyl)-3-(trimethylsilyl)prop-2-yn-1-yl 4-nitrobenzoate 
• 1044277-08-8 7-(azidomethyl)-4-(3-fluorophenyl)-2H-chromen-2-one 
• 1044277-04-4 (S)-1-ethyl-1-(trifluoromethyl)prop-2-yn-1-yl 4-nitrobenzoate 
• 1044277-07-7 7-(bromomethyl)-4-(3-fluorophenyl)-2H-chromen-2-one 
• 1044277-06-6 4-(3-fluorophenyl)-7-methyl-2H-chromen-2-one 

Relevant articles and documents

Convergent, fit-for-purpose, kilogram-scale synthesis of a 5-lipoxygenase inhibitor

Process research and development of a synthetic route towards a novel 5-lipoxygenase inhibitor is described. The synthetic route provided 1 in 27% yield in nine steps (seven steps in the longest linear sequence) and was performed on kilogram scale. The synthesis began with the preparation of the coumarin core via an efficient von Pechmann condensation. The triazole fragment was obtained via a regioselective copper-catalyzed [3 + 2] cycloaddition between a chiral alkyne and the coumarin azide.