104431-72-3Relevant articles and documents
Pyridine N-oxidation derivative as well as preparation method and application thereof
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Paragraph 0301; 0308-0311, (2019/08/06)
The invention relates to a pyridine N-oxidation derivative as well as a preparation method and an application thereof, in particular to a compound shown in a general formula (I), a preparation methodof the compound, pharmaceutical composition containing the compound and an application of the compound as a BRD4 inhibitor in treating related diseases such as cancer, inflammation, chronic liver diseases, diabetes, cardiovascular diseases, AIDS and the like, wherein in the general formula (I), all substituent groups are the same as definitions in the description.
A novel, nonsteroidal inhibitor of androgen binding to the rat androgen binding protein: Diethyl [[[3-(2,6-dimethyl-4-pyridinyl)-4-fluorophenyl]amino]methylene]propane dioate
Winneker,Wagner,Singh
, p. 129 - 132 (2007/10/02)
In vitro binding studies demonstrate the binding specificity of a series of 4-aryl-2,6-dimethylpyridines for the rat epididymal androgen binding protein (rABP). The compounds bound competitively to rABP but have very weak or no demonstrable affinity for r