1044596-89-5

Basic information

• Product Name: (R)-2-amino-3-(2,4-difluorophenoxy)propionic acid
• Synonyms: (R)-2-amino-3-(2,4-difluorophenoxy)propionic acid
• CAS NO: 1044596-89-5
• Molecular Weight: 217.172
• Mol File: 1044596-89-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-2-amino-3-(2,4-difluorophenoxy)propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-amino-3-(2,4-difluorophenoxy)propionic acid(1044596-89-5)
• EPA Substance Registry System: (R)-2-amino-3-(2,4-difluorophenoxy)propionic acid(1044596-89-5)

Safety Data

• Hazardous Substances Data: 1044596-89-5(Hazardous Substances Data)

Upstream product

• 367-27-1 2,4-difluorophenol 
• 5680-80-8 methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride 

Downstream Products

• 1044596-91-9 C₁₁H₈F₅NO₄ 
• 1184842-84-9 C₁₂H₁₃F₂NO₅ 
• 939759-01-0 (R)-3-amino-6,8-difluorochroman 
• 760173-05-5 (R)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydroimidazole-2-thione 
• 1393846-76-8 C₉H₇BrF₂O₂ 
• 1393846-82-6 C₁₂H₁₁BrF₂O₄ 
• 1393847-42-1 C₂₅H₃₂F₂N₂O₅ 
• 1393847-43-2 C₂₄H₂₅F₂N₃O₃S 
• 1161948-00-0 C₁₂H₁₂ClF₂NO₄ 
• 98130-56-4 2-bromo-4,6-difluorophenol 

Relevant articles and documents

Process research for multikilogram production of etamicastat: A novel dopamine β-hydroxylase inhibitor

In order to develop a manufacturing route to etamicastat, three synthetic approaches to the pivotal chiral 3-aminochroman intermediate have been studied as well as four methods for the construction of the 2-aminoethyl imidazolethione fragment. The evoluti

COMPOUNDS

This invention relates to new 6,8-difluorochroman-3-yl-1,3-dihydroimidazole-2-thiones, their preparation, and their use as a medicament.