760173-05-5

Usage

Uses

Used in Pharmaceutical Industry:
(R)-5-(2-Aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydroimidazole-2-thione is used as a potential therapeutic agent for mood disorders due to its possible interactions with the serotonin receptor.
Used in Antimicrobial Applications:
(R)-5-(2-Aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydroimidazole-2-thione is used as an antimicrobial agent due to its imidazole structure, which may exhibit antibacterial and antifungal properties.
Used in Antifungal Applications:
(R)-5-(2-Aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydroimidazole-2-thione is used as an antifungal agent due to its imidazole structure, which may exhibit antifungal properties.

Upstream product

• 677773-32-9 Etamicastat hydrochloride 
• 939759-01-0 (R)-3-amino-6,8-difluorochroman 
• 1043421-43-7 6,8-difluoro-2H-chromene-3-carbonitrile 
• 1151797-94-2 6,8-difluoro-2H-chromene-3-carboxamide 
• 1034001-13-2 methyl 6,8-difluoro-2H-chromen-3-yl-carbamate 
• 1034000-36-6 (R)-methyl 6,8-difluorochroman-3-ylcarbamate 
• 1044596-95-3 (R)-2-{2-[3-(6,8-difluorochroman-3-yl)-2-thioxo-2,3-dihydro-1H-imidazol-4-yl]ethyl}isoindole-1,3-dione 
• 1044596-89-5 (R)-2-amino-3-(2,4-difluorophenoxy)propionic acid 
• 1161948-00-0 C₁₂H₁₂ClF₂NO₄ 
• 1184842-84-9 C₁₂H₁₃F₂NO₅ 
• 1044597-03-6 (R)-6,8-difluorochroman-3-amine L-tartrate salt 
• 1083157-18-9 C₁₂H₁₁F₂NO₄ 
• 1034000-40-2 (R)-(6,8-difluorochroman-3-yl)carbamic acid ethyl ester 
• 367-27-1 2,4-difluorophenol 

Downstream Products

• 1080028-80-3 (R)-5-(2-(benzylamino)ethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione 

Relevant academic research and scientific papers

Process research for multikilogram production of etamicastat: A novel dopamine β-hydroxylase inhibitor

In order to develop a manufacturing route to etamicastat, three synthetic approaches to the pivotal chiral 3-aminochroman intermediate have been studied as well as four methods for the construction of the 2-aminoethyl imidazolethione fragment. The evoluti

PROCESS FOR THE PREPARATION OF (R) -5- (2-AMINOETHYL) -1- (6, 8-DIFLUOROCHROMAN-3-YL) -1, 3-DIHYDROIMIDAZOLE-2-THIONE

A process for making (R)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydroimidazole-2-thione and pharmaceutically acceptable salts thereof, and for making intermediates useful in the formation of said compound.

PROCESS FOR THE PREPARATION OF (R) -5- (2-AMINOETHYL) -1- (6, 8 -DI FLUOROCHROMAN- S -YL ) -1, 3-DIHYDROIMIDAZOLE-2-THIONE

A process for making (R)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydroimidazole-2-thione and pharmaceutically acceptable salts thereof, and for making intermediates useful in the formation of said compound.