1044637-38-8

Basic information

• Product Name: 2-(2-(4-chlorophenyl)-2-oxoethoxy)isoindoline-1,3-dione
• Synonyms: 2-(2-(4-chlorophenyl)-2-oxoethoxy)isoindoline-1,3-dione
• CAS NO: 1044637-38-8
• Molecular Weight: 315.713
• Mol File: 1044637-38-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-(2-(4-chlorophenyl)-2-oxoethoxy)isoindoline-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-(4-chlorophenyl)-2-oxoethoxy)isoindoline-1,3-dione(1044637-38-8)
• EPA Substance Registry System: 2-(2-(4-chlorophenyl)-2-oxoethoxy)isoindoline-1,3-dione(1044637-38-8)

Safety Data

• Hazardous Substances Data: 1044637-38-8(Hazardous Substances Data)

Upstream product

• 1073-67-2 4-vinylbenzyl chloride 
• 524-38-9 N-hydroxyphthalimide 

Downstream Products

• 136918-14-4 phthalimide 
• 4998-15-6 4-chlorophenylglyoxal 

Relevant articles and documents

Iron-Catalyzed Regioselective Oxo- and Hydroxy-Phthalimidation of Styrenes: Access to α-Hydroxyphthalimide Ketones

This paper describes the aerobic oxidation of styrenes catalyzed by iron(III) chloride (FeCl3) to form β-keto-N-alkoxyphthalimides in fair to good yields. This oxidative process employs mild conditions with green and atom efficient dioxygen (O2) as the oxidant.

Catalyst-controlled dioxygenation of olefins: An approach to peroxides, alcohols, and ketones

An efficient catalytic approach for the synthesis of substituted peroxides, alcohols, and ketones through a catalyst-controlled highly selective dioxygenation of olefins has been demonstrated. The reported methods are mild and practical, can be switched by the selection of different catalytic systems, and employ peroxide as an oxidant and a reagent at room temperature.

Cobalt Catalyst-Controlled Selective Dioxygenation of Styrenes Using N-Hydroxyphthalimide with Molecular Oxygen

A cobalt-catalyzed selective dioxygenation of styrenes with N-hydroxyphthalimide (NHPI) was developed using molecular oxygen as the terminal oxidant. Alcohol and ketone products can be selectively formed from identical substrates by catalyst control. The reaction was applicable to a broad range of styrenes and exhibited good functional group tolerance. It provided a method for preparation of 1,2-diol or α-hydroxyketone derivatives. (Figure presented.).

Electrochemical Oxidative Difunctionalization of Alkenes to Access α-Oxygenated Ketones

Dioxygenation of alkenes was developed by the combination of electrochemical synthesis and aerobic oxidation, leading to easy accessibility of α-oxygenated ketones in an eco-friendly fashion. Using air as the oxygen source and the absence of transition metals were the critical features of this protocol. A wide range of alkenes and N-hydroxyimides were found to be compatible and provided α-oxygenated ketones in moderate to high yields.