104478-97-9

Basic information

• Product Name: N-(4-amino-2-methoxyphenyl)benzamide
• Synonyms: N-(4-amino-2-methoxyphenyl)benzamide
• CAS NO: 104478-97-9
• Molecular Formula: C₁₄H₁₄N₂O₂
• Molecular Weight: 242.27316
• Mol File: 104478-97-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-amino-2-methoxyphenyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-amino-2-methoxyphenyl)benzamide(104478-97-9)
• EPA Substance Registry System: N-(4-amino-2-methoxyphenyl)benzamide(104478-97-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 104478-97-9(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 97-52-9 2-methoxy-4-nitrophenylamine 
• 5395-00-6 N-(2-methoxyphenyl)benzamide 
• 38259-78-8 N-(2-methoxy-4-nitrophenyl)benzamide 

Downstream Products

• 104479-06-3 C₁₉H₂₀N₄O₆ 
• 804476-61-7 N-[2-methoxy-4-(p-tolylsulfonylamino)phenyl]thiobenzamide 
• 804476-60-6 N-[2-methoxy-4-(p-tolylsulfonylamino)phenyl]benzamide 

Relevant articles and documents

Amide compound and derivative thereof, preparation method, pharmaceutical composition and application thereof

The invention discloses an amide compound and derivative thereof, a preparation method, a pharmaceutical composition and application thereof. The structure of the amide compound is shown as a formula (I). The derivatives of theamide compound relate to a stereoisomer, a tautomer, a metabolite, a metabolic precursor, a prodrug, a solvate, a salt of the solvate, a crystal, a pharmaceutically acceptable salt or a mixture of the above of theamide compound. The amide compound and the derivative thereof have an efficient inhibition effect on indoleamine 2, 3-dioxygenase 1, and can be used for preparing medicines for treating indoleamine 2, 3-dioxygenase 1 mediated immunosuppression related diseases, the prepared medicine can exert the medicine effect at the molecular level and is wide in application, and the synthesis method of the compound is simple, convenient and easy to operate.

Synthesis of benzothiazoles via ipso substitution of ortho- methoxythiobenzamides

An efficient route to the synthesis of benzothiazoles from orthoo-methoxythiobenzamides via the ipso substitution of an aromatic methoxy group is presented, and the mechanism of the Jacobson synthesis of benzothiazoles is further investigated.