104505-74-0

Upstream product

• 97195-31-8 cinnamic acid-(2-mercapto-anilide) 
• 103-36-6 ethyl 3-phenyl-2-propenoate 
• 137-07-5 2-amino-benzenethiol 
• 16503-53-0 2-bromo-3-phenylpropanoic acid 
• 93102-82-0 2-acetyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazine 
• 100-39-0 benzyl bromide 
• 29476-22-0 2,3-dihydro-2-phenyl-1,5-benzothiazepin-4(5H)-one 
• 70288-60-7 methyl 2-bromo-3-phenylpropionate 
• 62-53-3 aniline 
• 101308-40-1 ethyl 2-bromo-3-phenylpropionate 
• 118670-85-2 (2E)-N-(2-iodophenyl)-3-phenylprop-2-enamide 
• 55043-20-4 2-(phenylmethylidene)-3,4-dihydro-2H-1,4-benzothiazin-3-one 
• 935524-52-0 2-(2-amino-phenylsulfanyl)-3-phenyl-propionic acid methyl ester 

Downstream Products

• 935524-53-1 2-Benzyl-3,4-dihydro-2H-1,4-benzothiazine 

Relevant academic research and scientific papers

Synthesis of Oxazine, Thiazine, and Quinoxaline Derivatives Containing a Benzyl Fragment from 3-Aryl-2-Bromopropanoic Acids and Their Esters

Abstract: 3-Aryl-2-bromopropanoic acid esters reacted with o-phenylenediamine, 2-sulfanylaniline, and L-cysteine to give quinoxaline, 1,4-thiazine, and thiomorpholine derivatives, respectively, containing an aryl-methyl substituent. Analogous 1,4-benzoxaz

Copper-catalyzed highly selective synthesis of 2-benzyl- and 2-benzylidene-substituted benzo[: B] thiazinones from 2-iodophenylcinnamamides and potassium sulfide

An efficient and practical procedure for the synthesis of 2-benzyl- and 2-benzylidene-substituted benzo[b]thiazinones from easily available 2-iodophenylcinnamamides and potassium sulfide has been developed. In the presence of DBU, the reaction proceeds vi

LXR modulators

A compound of formula I wherein A, X, q, R1, R2a, R2b, R2c, R3a, and R3b are defined herein.

Reaction of N,N'-Dialkyldithiodianilines with β-Ketoesters. A New Synthesis of N-Alkyl-2-acyl-3-oxo-3,4-dihydro-1,4-benzothiazines

The title compounds 3a-j together with the N-alkylacylketene S,N-acetals 12a-j were obtained by reaction of N,N'-dialkyldithiodianilines with β-ketoesters compounds.A posible reaction pathway is suggested.

Rearrangements and Complex Eliminations with 1,5-Benzothiazepin-4-ones

The 1,5-benzothiazepin-4-ones 3, 5, and 7 - 10 are pyrolyzed (with proton catalysis in part).New or rarely documented rearrangements and complex eliminations occur.These are classified and mechanistically discussed.The products and by-products are spectroscopically characterized (IR, UV, NMR, MS).Their configurations are elucidated via photolysis experiments. 4 photodimerizes in solution and in the crystalline state with great ease to give 14. 11 is remarkably insensitive towards hydrolysis.