1045821-71-3

Basic information

• Product Name: N-[(trifluoromethyl)sulfanyl]aniline
• Synonyms: N-[(trifluoromethyl)sulfanyl]aniline
• CAS NO: 1045821-71-3
• Molecular Weight: 193.193
• Mol File: 1045821-71-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: N-[(trifluoromethyl)sulfanyl]aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(trifluoromethyl)sulfanyl]aniline(1045821-71-3)
• EPA Substance Registry System: N-[(trifluoromethyl)sulfanyl]aniline(1045821-71-3)

Safety Data

• Hazardous Substances Data: 1045821-71-3(Hazardous Substances Data)

Upstream product

• 421-17-0 Trifluoromethylsulfenyl chloride 
• 62-53-3 aniline 
• 38078-09-0 diethylamino-sulfur trifluoride 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 719-98-2 N-((trifluoromethyl)thio)isoindoline-1,3-dione 
• 66476-44-6 N-methyl-N-phenyl-S-(trifluoromethyl)thiohydroxylamine 
• 27607-77-8 trimethylsilyl trifluoromethanesulfonate 

Downstream Products

• 1201679-96-0 1-methyl-6-[(trifluoromethyl)thio]cyclohexene 
• 1045823-45-7 2-[(trifluoromethyl)thio]dodecyl 4-methylbenzenesulfonate 
• 1045822-63-6 1-{[(trifluoromethyl)thio]methyl}undecyl 4-methylbenzenesulfonate 
• 1045823-47-9 4-phenyl-2-[(trifluoromethyl)thio]butyl 4-methylbenzenesulfonate 
• 1045822-65-8 3-phenyl-1-{[(trifluoromethyl)thio]methyl}propyl 4-methylbenzenesulfonate 
• 1045822-74-9 C₁₇H₂₅F₃O₄S₂ 
• 1394825-75-2 4-methyl-N-(2-(2-(trifluoromethylthio)-1H-indol-3-yl)ethyl)benzenesulfonamide 
• 1394825-78-5 benzyl 2-(2-(trifluoromethylthio)-1H-indol-3-yl)ethylcarbamate 
• 1454762-77-6 2,6-dimethyl-3-phenyl-4-((trifluoromethyl)thio)-2H-benzo[e][1,2]thiazine 1,1-dioxide 
• 1454762-78-7 3-(4-chlorophenyl)-2,6-dimethyl-4-((trifluoromethyl)thio)-2H-benzo[e][1,2]thiazine 1,1-dioxide 
• 1454762-79-8 3-(4-methoxyphenyl)-2,6-dimethyl-4-((trifluoromethyl)thio)-2H-benzo[e][1,2]thiazine 1,1-dioxide 
• 1454762-80-1 6-chloro-2-methyl-3-phenyl-4-((trifluoromethyl)thio)-2H-benzo[e][1,2]thiazine 1,1-dioxide 
• 1454762-81-2 6-methoxy-2-methyl-3-phenyl-4-((trifluoromethyl)thio)-2H-benzo[e][1,2]thiazine 1,1-dioxide 
• 1454762-82-3 2-methyl-3-phenyl-4-((trifluoromethyl)thio)-2H-benzo[e][1,2]thiazine 1,1-dioxide 

Relevant articles and documents

Multigram Scale Syntheses of First and Second Generation of Trifluoromethanesulfenamide Reagents

Trifluoromethanesulfenamide reagents constitute a family of very efficient reagents to trifluoromethylthiolate various molecules. Optimized syntheses have been developed to easily obtain, in a reproducible manner, large quantities of these reagents, with good overall yields. Up to 84 g have already been obtained, at a reasonable cost.

For the production of sulfur-hydrogen reagent, synthetic method and its application

The invention discloses a trifluoromethylthio reagent as well as a synthetic method and application thereof and provides a compound I and a preparation method of the compound I. The preparation method comprises the step: reacting a compound 1a with trifluoromethylthio silver, so as to obtain the compound 1, wherein the reaction is as shown in the specification. The invention further provides application of the compound 1 as the trifluoromethylthio reagent. The compound 1 can react with amine compounds, thiol or phenolic compounds to generate the compound containing trifluoromethylthio. The trifluoromethylthio reagent 1 has the beneficial effects of high efficiency, conversion rate and yield, mild reaction conditions, low production cost and wide applicable range and is applicable to industrial production.

N-trifluoromethylthiosaccharin: An easily accessible, shelf-stable, broadly applicable trifluoromethylthiolating reagent

A new, electrophilic trifluoromethylthiolating reagent, N-trifluoromethylthiosaccharin, was developed and can be synthesized in two steps from saccharin within 30minutes. N-trifluoromethylthiosaccharin is a powerful trifluoromethylthiolating reagent and allows the trifluoromethylthiolation of a variety of nucleophiles such as alcohols, amines, thiols, electron-rich arenes, aldehydes, ketones, acyclic β-ketoesters, and alkynes under mild reaction conditions. 'Sacch'ed out: A new, electrophilic trifluoromethylthiolating reagent, N-trifluoromethylthiosaccharin (1) can be synthesized in two steps from saccharin within 30minutes. The reagent 1 allows the trifluoromethylthiolation of a variety of nucleophiles such as alcohols, amines, thiols, electron-rich arenes, aldehydes, ketones, acyclic β-ketoesters, and alkynes under mild reaction conditions.