104599-83-9

Basic information

• Product Name: 2-(2,4-Dichlor-5-fluorbenzoyl)-3-propylaminoacrylsaeure-ethylester
• CAS NO: 104599-83-9
• Molecular Weight: 348.201
• Mol File: 104599-83-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2,4-Dichlor-5-fluorbenzoyl)-3-propylaminoacrylsaeure-ethylester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,4-Dichlor-5-fluorbenzoyl)-3-propylaminoacrylsaeure-ethylester(104599-83-9)
• EPA Substance Registry System: 2-(2,4-Dichlor-5-fluorbenzoyl)-3-propylaminoacrylsaeure-ethylester(104599-83-9)

Safety Data

• Hazardous Substances Data: 104599-83-9(Hazardous Substances Data)

Upstream product

• 86483-51-4 ethyl 2,4-dichloro-5-fluoro-benzoyl-acetate 
• 86483-50-3 diethyl 2,4-dichloro-5-fluoro-benzoyl-malonate 
• 86393-34-2 2,4-dichloro-5-fluorobenzoyl chloride 

Relevant articles and documents

Cycloaracylation of Enamines, I. - Synthesis of 4-Quinolone-3-carboxylic Acids

Starting with o-halobenzoyl chlorides 4 and open-chain secondary enamines 5, a new synthesis of 4-quinolone-3-carboxylic acids 12 is described.The reaction of 7-haloquinolone-3-carboxylic acids 12a-k with aliphatic amines 14 produces highly active antibacterial 7-aminoquinolone-3-carboxylic acids 15.The main product of the 1-cyclopropyl series, "ciprofloxacin" (15a), is being developed as a broad-spectrum chemotherapeutic agent.