10463-10-2

Usage

Uses

Used in Agricultural Industry:
1,2,3,4,5-Pentachloro-6-ethoxybenzene is used as a fungicide for protecting crops from fungal infections, ensuring higher crop yields and quality. However, due to its toxic nature to aquatic organisms and potential harm to the environment, its use has been subject to regulation and restriction in certain countries.
Used in Environmental and Health Regulations:
1,2,3,4,5-Pentachloro-6-ethoxybenzene is considered in the context of environmental and health regulations as a potential human carcinogen. Its exposure has been linked to liver and kidney damage, prompting the need for stringent controls on its usage and disposal to mitigate risks to both human health and the ecosystem.

InChI:InChI=1/C8H5Cl5O/c1-2-14-8-6(12)4(10)3(9)5(11)7(8)13/h2H2,1H3

Upstream product

• 118-74-1 hexachlorobenzene 
• 856343-24-3 4-ethoxy-2,3,5,6-tetrachloro-aniline 
• 87-86-5 Pentachlorophenol 
• 75-03-6 ethyl iodide 
• 141-52-6 sodium ethanolate 
• 599-52-0 2,3,4,4,5,6-hexachlorocyclohexa-2,5-dien-1-one 
• 1569262-64-1 ethyl N-tert-butyl-4-nitrobenzenesulfonimidate 

Downstream Products

• 73342-39-9 2,3,4,5-Tetrachlor-phenetol 
• 56818-02-1 2,3,4,6-tetrachloro-phenetole 
• 6936-41-0 2,3,5,6-tetrachloro-phenetole 

Relevant academic research and scientific papers

SNAAP sulfonimidate alkylating agent for acids, alcohols, and phenols 1

Stable, crystalline ethyl N-tert-butyl-4-nitrobenzenesulfonimidate has been prepared in high yield by direct O-ethylation of N-tert-butyl-4- nitrobenzenesulfonamide with iodoethane and silver(I) oxide in dichloromethane. This sulfonimidate directly ethylates various acids to esters; the stronger the acid, the faster it alkylates and in higher yield. It readily ethylates alcohols and phenols to ethers at room temperature in the presence of tetrafluoroboric acid catalyst without molecular rearrangements or racemization. We have defined these reactions as SNAAP alkylations: [substitution, nucleophilic of acids, alcohols and phenols]. The hard sulfonimidate alkylating agent is chemoselective, preferring oxygen > nitrogen > sulfur. The sulfonamide byproduct of alkylation is readily recycled to the sulfonimidate. Georg Thieme Verlag Stuttgart . New York.