104756-71-0Relevant articles and documents
Synthesis and hypolipidemic activity of diesters of arylnaphthalene lignan and their heteroaromatic analogs
Kuroda, Tooru,Kondo, Kazuhiko,Iwasaki, Tameo,Ohtani, Akio,Takashima, Kohki
, p. 678 - 684 (2007/10/03)
A series of diesters of arylnaphthalene lignan and their heteroaromatic analogs were synthesized and evaluated for hypolipidemic activity. The diesters with modifications at C-3 showed excellent hypocholesterolemic and high-density lipoprotein (HDL) cholesterol-elevating activities. Structure- activity analysis indicated that the 2-pyridylmethyl ester 51 has the optimum activity.
Arylnaphthalene lignans as novel series of hypolipidemic agents raising high-density lipoprotein level
Iwasaki,Kondo,Nishitani,Kuroda,Hirakoso,Ohtani,Takashima
, p. 1701 - 1705 (2007/10/03)
A series of arylnaphthalene lignans were synthesized and tested for hypolipidemic activity. The most potent compound (4b) (TA-7552) not only reduced serum cholesterol, but also increased high-density lipoproteins cholesterol in rats. The effective dose of
Process for preparing a naphthalene derivative
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, (2008/06/13)
A novel process for preparing a naphthalene derivative of the formula: STR1 wherein R1, R2, R3, R4, R5, R6 and R7 are a lower alkyl group, and an intermediate thereof is disclose
A process for preparing a naphthalene derivative
-
, (2008/06/13)
A novel process for preparing a naphthalene derivative of the formula: wherein R1, R2, R3, R4, R5, R6 and R7 are a lower alkyl group, and an intermediate thereof is disclosed. Said naphthalene derivative (I) and
Naphthalene derivatives and composition and methods of use, and aldehyde intermediates
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, (2008/06/13)
Naphthalene derivative of the formula: STR1 wherein R1 is hydrogen atom or a lower alkoxycarbonyl and R2 is a lower alkoxycarbonyl, or R1 and R2 are combined together to form a group of the formula: STR2 each of
Novel naphthalene derivative
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, (2008/06/13)
Naphthalene derivative of the formula: STR1 wherein Ring A is a substituted or unsubstituted benzene ring; each of R1 and R2 is a group of the formula: --OR5, --NHR5 or STR2 or either one of R1 and R
Alkoxynaphthalene derivatives
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, (2008/06/13)
Naphthalene derivative of the formula: STR1 wherein R1 is hydrogen atom or a lower alkoxycarbonyl and R2 is a lower alkoxycarbonyl, or R1 and R2 are combined together to form a group of the formula: STR2 each of