104880-96-8 Usage
Description
(R)-2-Amino-3-(3-fluorophenyl)propionic acid ethyl ester, commonly known as (R)-Flurbiprofen, is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the propionic acid derivatives class. It is an enantiomer of Flurbiprofen and is characterized by its higher potency and longer duration of action compared to the racemic mixture. This chemical compound works by inhibiting the enzymes cyclooxygenase-1 and -2, which are responsible for the production of prostaglandins that cause pain and inflammation.
Uses
Used in Pharmaceutical Industry:
(R)-2-Amino-3-(3-fluorophenylpropionicacidethylester is used as an analgesic and anti-inflammatory agent for the treatment of various conditions such as rheumatoid arthritis, osteoarthritis, and other inflammatory disorders. Its unique chemical structure and pharmacological properties make it a valuable therapeutic agent in the management of pain and inflammation.
Used in Pain Management:
(R)-2-Amino-3-(3-fluorophenylpropionicacidethylester is used as a pain reliever to alleviate pain associated with various conditions, including arthritis and other inflammatory disorders. Its ability to inhibit the production of prostaglandins makes it an effective option for pain management.
Used in Inflammation Treatment:
(R)-2-Amino-3-(3-fluorophenylpropionicacidethylester is used as an anti-inflammatory agent to reduce inflammation caused by various conditions, such as arthritis and other inflammatory disorders. Its inhibition of cyclooxygenase enzymes helps to decrease the production of prostaglandins, which are responsible for inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 104880-96-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,8,8 and 0 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 104880-96:
(8*1)+(7*0)+(6*4)+(5*8)+(4*8)+(3*0)+(2*9)+(1*6)=128
128 % 10 = 8
So 104880-96-8 is a valid CAS Registry Number.
104880-96-8Relevant articles and documents
IMIDAZOPYRAZINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND THEIR USES AS LUCIFERINS
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Page/Page column 60; 63, (2018/11/22)
The present invention is in the field of bioluminescence in biology and/or medicine. In particular, the invention provides imidazopyrazine derivatives, processes for preparation thereof, and their uses as luciferins.
Pd-catalyzed directed ortho -C-H alkenylation of phenylalanine derivatives
García-Rubia, Alfonso,Laga, Eduardo,Cativiela, Carlos,Urriolabeitia, Esteban P.,Gómez-Arrayás, Ramón,Carretero, Juan C.
, p. 3321 - 3331 (2015/03/30)
A practical Pd-catalyzed ortho-olefination of enantioenriched N-(SO2Py)-protected aryl-alanine and norephedrine derivatives with electron-deficient alkenes has been developed using N-fluoro-2,4,6-trimethylpyridinium triflate as the terminal oxidant. The reaction occurs efficiently with excellent monosubstitution selectivity and without loss of enantiopurity. This cross-coupling proved to be broad in scope, tolerating a variety of steric and electronic changes to both coupling partners. Removal of the directing group under mild conditions provides access to optically active tetrahydroisoquinoline-3-carboxylic acid derivatives (Tics) with good diastereocontrol and with very small erosion of enantiomeric purity.
Method of treating nausea and vomiting with certain substituted-phenylalkylamino (and aminoacid) derivatives and other serotonin depleting agents
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, (2008/06/13)
A method for the treatment of emesis in a mammal, which method comprises administering to said mammal an emesis inhibiting amount of a compound which depletes serotonin in the brain of mammals; among which are compounds having the formula: STR1 wherein, R is selected from hydrogen, loweralkyl, trifluoromethyl, carboxyl, or loweralkoxycarbonyl; R1 and R2 are hydrogen or loweralkyl; Z is trifluoromethyl or halogen; the optical isomers and pharmaceutically acceptable salts thereof; two of the preferred compounds of the invention are fenfluramine and norfenfluramine.
