104916-41-8

Basic information

• Product Name: 4-Methoxy-3,5-diMethylpicolinonitrile
• Synonyms: 4-Methoxy-3,5-diMethylpicolinonitrile;3,5-Dimethyl-4-methoxypyridine-2-carbonitrile;4-methoxy-3,5-dimethylpyridine-2-carbonitrile
• CAS NO: 104916-41-8
• Molecular Formula: C₉H₁₀N₂O
• Molecular Weight: 162.1885
• Mol File: 104916-41-8.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Methoxy-3,5-diMethylpicolinonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxy-3,5-diMethylpicolinonitrile(104916-41-8)
• EPA Substance Registry System: 4-Methoxy-3,5-diMethylpicolinonitrile(104916-41-8)

Safety Data

• Hazardous Substances Data: 104916-41-8(Hazardous Substances Data)

Usage

Uses

4-Methoxy-3,5-dimethylpicolinonitrile has been used as a reactant in the synthesis of 2-[(3,5-dimethyl-4-methoxypyridinyl)alkyl]benzothiazolidine derivatives as gastric H+/K+-ATPase inhibitor1.

Upstream product

• 86604-78-6 (4-methoxy-3,5-dimethylpyridin-2-yl)methanol 
• 110464-72-7 4-methoxy-3,5-dimethyl-2-pyridinecarboxaldehyde 
• 187222-13-5 3,5-Dimethyl-2-ethoxycarbonyl-4-pyrone 
• 187222-20-4 2-Carboxamide-3,5-Dimethyl-4(1H)-Pyridone 
• 187222-12-4 3,5-dimethyl-4-oxo-4H-pyran-2-carboxylic acid 
• 187222-11-3 1-ethoxy-2-methylpent-1-en-3-one 
• 50421-81-3 1-hydroxy-2-methyl-1-penten-3-one 
• 187222-21-5 2-Carboxamide-3,5-Dimethyl-4-Methoxypyridine 

Downstream Products

• 130000-78-1 (4-methoxy-3,5-dimethylpyridin-2-yl)methanamine 
• 86604-75-3 2-(chloromethyl)-4-methoxy-3,5-dimethylpyridine hydrochloride 

Relevant articles and documents

A Transition-Metal-Free One-Pot Cascade Process for Transformation of Primary Alcohols (RCH2OH) to Nitriles (RCN) Mediated by SO2F2

A new transition-metal-free one-pot cascade process for the direct conversion of alcohols to nitriles was developed without introducing an “additional carbon atom”. This protocol allows transformations of readily available, inexpensive, and abundant alcohols to highly valuable nitriles.

Process for preparing 2-cyano-3,5-dimethyl-4-methoxypyridine

A process of preparing 2-cyano-3,5-dimethyl-4-methoxypyridine. The process includes the steps of: acylating 2-methyl-1-penten-1-alkoxy-3-one to obtain 2-alkoxycarbonyl-3,5-dimethyl-4-pyrone; ammonolyzing 2-alkoxycarbonyl-3,5-dimethyl-4-pyrone to obtain 2-carboxamido-3,5-dimethyl-4(1H)-pyridone; methylating 2-carboxamido-3,5-dimethyl-4(1H)-pyridone to obtain 2-carboxamido-3,5-dimethyl-4-methoxypyridine; and dehydrating said 2-carboxamido-3,5-dimethyl-4-methoxypyridone to obtain 2-cyano-3,5-dimethyl-4-methoxypyridine.