187222-13-5

Basic information

• Product Name: 3,5-DiMethyl-2-(ethoxycarbonyl)-4-pyrone
• Synonyms: 3,5-DiMethyl-2-(ethoxycarbonyl)-4-pyrone
• CAS NO: 187222-13-5
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.19988
• Product Categories: Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 187222-13-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Dichloromethane, Methanol
• CAS DataBase Reference: 3,5-DiMethyl-2-(ethoxycarbonyl)-4-pyrone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DiMethyl-2-(ethoxycarbonyl)-4-pyrone(187222-13-5)
• EPA Substance Registry System: 3,5-DiMethyl-2-(ethoxycarbonyl)-4-pyrone(187222-13-5)

Safety Data

• Hazardous Substances Data: 187222-13-5(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Solid

Uses

Omeprazole (O635000) intermediate.

Upstream product

• 187222-11-3 1-ethoxy-2-methylpent-1-en-3-one 
• 50421-81-3 1-hydroxy-2-methyl-1-penten-3-one 
• 95-92-1 oxalic acid diethyl ester 
• 64-17-5 ethanol 
• 187222-12-4 3,5-dimethyl-4-oxo-4H-pyran-2-carboxylic acid 

Downstream Products

• 187222-15-7 N-benzyl-2-ethoxycarbonyl-3,5-dimethyl-4-pyridone 
• 187222-17-9 4-Chloro-2-ethoxycarbonyl-3,5-Lutidine 
• 187222-18-0 2-methoxycarbonyl-3,5-dimethyl-4-methoxypyridine 
• 104916-41-8 3,5-dimethyl-4-methoxy-2-cyanopyridine 
• 86604-78-6 (4-methoxy-3,5-dimethylpyridin-2-yl)methanol 

Relevant articles and documents

Organic compound synthesis

A strategy for synthesising omeprazole 10 starting from compound 1 as shown in the diagram. Individual method steps 1->2, 2->3, 3->4, 4->5, 5->6, 6->7, and intermediate compounds 2, 3, 4, 5, 6 and 9 are also claimed as new.

Process of preparing 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine

A process of preparing 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine including the steps of acylating 2-methyl-1-penten-1-alkoxy-3-one to obtain 2-alkoxycarbonyl-3,5-dimethyl-4-pyrone; ammonolyzing 2-alkoxycarbonyl-3,5-dimethyl-4-pyrone to obtain 2-alkoxycarbonyl-3,5-dimethyl-4(1H)-pyridone; halogenating 2-alkoxycarbonyl-3,5-dimethyl-4(1H)-pyridone to obtain 2-alkoxycarbonyl-4-halo-3,5-dimethylpyridine; methoxylating 2-alkoxycarbonyl-4-halo-3,5-dimethylpyridine to obtain 2-methoxycarbonyl-3,5-dimethyl-4-methoxypyridine; and reducing 2-methoxycarbonyl-3,5-dimethyl-4-methoxypyridine to obtain 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine.