104944-19-6

Basic information

• Product Name: Z-S-Pro-R-Val-OtBu
• Synonyms: Z-S-Pro-R-Val-OtBu
• CAS NO: 104944-19-6
• Molecular Weight: 404.506
• Mol File: 104944-19-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Z-S-Pro-R-Val-OtBu(CAS DataBase Reference)
• NIST Chemistry Reference: Z-S-Pro-R-Val-OtBu(104944-19-6)
• EPA Substance Registry System: Z-S-Pro-R-Val-OtBu(104944-19-6)

Safety Data

• Hazardous Substances Data: 104944-19-6(Hazardous Substances Data)

Upstream product

• 640-68-6 D-Val-OH 
• 5618-96-2 Z-S-Pro-OH 
• 13518-40-6 t-butyl D-valinate hydrochloride 

Downstream Products

• 51827-16-8 Z-S-Pro-R-Val-OH 
• 104944-22-1 Z-S-Pro-R-Val-S-Pro-OtBu 

Relevant articles and documents

STUDIES ON AMINO ACIDS AND PEPTIDES X. HPLC-MEDIATED TEST OF 2,4-BIS(4-METHOXYPHENYL)-1,3,2,4-DITHIADIPHOSPHETANE 2,4-DISULFIDE (LAWESSONS'S REAGENT) AS A RACEMIZATIONFREE COUPLING REAGENT IN PEPTIDE SYNTHESIS

The easily available 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide (Lawesson's Reagent), 1, has been tested as a coupling reagent for racemization in peptide synthesis.The assay procedure is separation of stereomeric products by HPLC.Z-S-Pro-S-Val-S-Pro-OtBu and Z-S-Leu-S-Phe-S-Val-OtBu have been used as test peptides in 2+1 segment couplings, and only a small amount of epimerization (0.5 and 0.1percent, respectively) has been observed.