5618-96-2

Basic information

• Product Name: 1-[(BENZYLOXY)CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID
• Synonyms: Z-DL-PROLINE;Z-DL-PRO-OH;N-Cbz-DL-proline;1-Cbz-pyrrolidine-2-carboxylic acid;1-[(benzyloxy)carbonyl]pyrrolicine-2-carboxylic acid;1,2-Pyrrolidinedicarboxylicacid, 1-(phenylmethyl) ester;N-Benzyloxycarbonyl-DL-proline;1-[(BENZYLOXY)CARBONYL]PROLINE
• CAS NO: 5618-96-2
• Molecular Formula: C₁₃H₁₅NO₄
• Molecular Weight: 249.26
• Product Categories: Carboxylic Acids;Pyrrolidines;Cbz-Amino acid series;Carboxylic Acids
• Mol File: 5618-96-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 101-102 °C(Solv: ethyl ether (60-29-7); ligroine (8032-32-4))
• Boiling Point: 432.3 °C at 760 mmHg
• Flash Point: 215.3 °C
• Appearance: /
• Density: 1.309 g/cm³
• Storage Temp.: Store at RT.
• PKA: 3.99±0.20(Predicted)
• CAS DataBase Reference: 1-[(BENZYLOXY)CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(BENZYLOXY)CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID(5618-96-2)
• EPA Substance Registry System: 1-[(BENZYLOXY)CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID(5618-96-2)

Safety Data

• Hazardous Substances Data: 5618-96-2(Hazardous Substances Data)

Usage

General Description

1-[(benzyloxy)carbonyl]pyrrolidine-2-carboxylic acid is a chemical compound with the molecular formula C16H19NO5. It is a white to off-white solid that is used in organic synthesis as a protecting group for amino acids. The compound consists of a pyrrolidine ring with a carboxylic acid and a benzyloxy carbonyl group attached. It is commonly used in the synthesis of peptide and protein molecules to protect the amino group of the amino acids from unwanted reactions. The compound is stable under normal conditions and is a valuable reagent in organic chemistry for various applications.

Upstream product

• 501-53-1 benzyl chloroformate 
• 147-85-3 (S)-proline 
• 147-85-3 L-proline 
• 75819-24-8 3-benzyloxycarbonyl-2-oxazolone 

Downstream Products

• 125705-53-5 4-(α-Benzoyloxycarbonyl-L-prolyl)amino-2-nitroaniline 
• 125705-71-7 5(6)-(α-Benzyloxycarbonyl-L-prolyl)amino-2-methoxycarbonyl-amino benzimidazole 
• 125705-62-6 4-(α-Benzyloxycarbonyl-L-prolyl)amino-1,2-phenylenediamine 
• 104944-22-1 Z-S-Pro-R-Val-S-Pro-OtBu 
• 51827-16-8 Z-S-Pro-R-Val-OH 
• 22348-32-9 (S)-diphenylprolinol 
• 104944-19-6 Z-S-Pro-R-Val-OtBu 
• 118059-29-3 Z-D-Pro-thiazolidine 
• 50888-84-1 Z-D-Pro-pyrrolidine 
• 838-85-7 diphenyl hydrogen phosphate 
• 6479-37-4 Pyrrolidine-1,2-dicarboxylic acid 2-benzhydryl ester 1-benzyl ester 
• 2766-31-6 2-(Ethoxycarbonylmethyl-carbamoyl)-pyrrolidine-1-carboxylic acid benzyl ester 
• 5211-23-4 N-(benzyloxycarbonyl)-(S)-proline methyl ester 
• 127560-06-9 Z-Pro-oxazolidine 

Relevant articles and documents

An Efficient and Catalytically Enantioselective Route to (S)-(-)-Phenyloxirane

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