104960-62-5

Upstream product

• 17368-73-9 N-acetyl-2-chloroacetamide 
• 104960-49-8 2-thioxo-6-phenyl-4-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile 
• 104960-54-5 4-trifluoromethyl-6-phenyl-3-cyano-2-pyridylthioacetic acid 
• 104960-56-7 3-amino-2-carboxy-4-trifluoromethyl-6-phenylthieno<2,3-b>pyridine 
• 82959-36-2 1-benzoyl-2-(1-morpholino)-3,3,3-trifluoro-1-propene 
• 326-06-7 1-Phenyl-4,4,4-trifluorobutane-1,3-dione 
• 104960-61-4 6-methyl-4-trifluoromethyl-2-phenylpyrido<2',3':5,4>thieno<3,2-d><1,3>-8-oxazinone 

Relevant academic research and scientific papers

N-acetylchloroacetamide in the synthesis of functionally-substituted pyrido[3′,2′:4,5]-thieno[3,2-d]pyrimidin-4(3H)-ones

3-Cyano-2(1H)-pyridinethiones react with N-acetylchloroacetamide in ethanol in the presence of KOH to give pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-ones. 1997 Plenum Publishing Corporation.

CYCLIZATION OF NITRILES. XVIII. SYNTHESIS AND SOME TRANSFORMATIONS OF 6-ARYL-4-TRIFLUOROMETHYL-3-CYANO-2(1H)-PYRIDINETHIONES

The reaction of 3-benzoyl- and 3-(2-thenoyl)-1,1,1-trifluoroacetone and also of 1-benzoyl- and 1-(2-thenoyl)-2-(1-morpholino)-3,3,3-trifluoro-1-propenes with cyanothioacetamide provides a convenient method for the production of 6-phenyl- and 6-(2-thienyl)-4-trifluoromethyl-3-cyano-2(1H)-pyridine thiones, which are used in the synthesis of substituted 3-aminothienopyridines and other condensed heterocyclic systems.