105041-05-2

Upstream product

• 2078-20-8 (E)-trimethylsilyl 3-phenylacrylate 
• 140-10-3 (E)-3-phenylacrylic acid 
• 621-82-9 Cinnamic acid 

Downstream Products

• 861350-38-1 2-diazo-3-oxo-5-phenyl-pent-4-enoic acid methyl ester 
• 4192-77-2 ethyl cinnamate 
• 104886-35-3 (E)-3-Phenyl-acrylic acid 2-iodo-3-methoxy-phenyl ester 
• 6750-98-7 (E)-N-cyclohexylcinnamamide 
• 873960-38-4 4-fluoro-2-nitrophenyl (2E)-3-phenylprop-2-enyl ether 
• 18903-01-0 trans-1-cinnamylpiperazine 
• 126201-33-0 (1E,5E)-1,6-diphenylhexa-1,5-diene-3,4-dione 

Relevant academic research and scientific papers

A mild and efficient reaction for conversion of carboxylic acids into acid bromides with ethyl tribromoacetate/triphenylphosphine under acid-free conditions

Acid bromides were prepared efficiently from carboxylic acids with readily available ethyl tribromoacetate and triphenylphosphine at room temperature under neutral conditions. The present process is applicable to the preparation of various acid bromides from aromatic and aliphatic carboxylic acids. Aromatic carboxylic acids were found to be more reactive than aliphatic carboxylic acids under reaction conditions.

Triphenylphosphine-2,4,4,6-tetrabromo-2,5-cyclohexadienone complex as a reagent for preparation of carboxylic acid bromides

Triphenylphosphine-2,4,4,6-tetrabromo-2,5-cyclohexadienone complex was successfully used as a new reagent for the synthesis of carboxylic acid bromides which were isolated as individual substances or were identified by conversion into the corresponding anilides. The reaction is chemoselective, and it can be applied to polyfunctional compounds, e.g., hydroxy acids.