105080-50-0 Usage
Molecular structure
A complex compound with a long and specific molecular structure.
Type
Synthetic dipeptidyl peptidase-4 (DPP-4) inhibitor.
Application
Used in the treatment of type 2 diabetes.
Mechanism of action
Inhibits the enzyme DPP-4, which helps regulate blood sugar levels by increasing the levels of incretin hormones.
Specificity
Precise molecular structure allows it to specifically target and inhibit the DPP-4 enzyme.
Effectiveness
Effective treatment for diabetes.
Chemical composition
Includes valine, proline, benzoyl, chlorophenylsulfonyl, and trifluoroacetyl groups.
Check Digit Verification of cas no
The CAS Registry Mumber 105080-50-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,0,8 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 105080-50:
(8*1)+(7*0)+(6*5)+(5*0)+(4*8)+(3*0)+(2*5)+(1*0)=80
80 % 10 = 0
So 105080-50-0 is a valid CAS Registry Number.
105080-50-0Relevant academic research and scientific papers
Inhibition of human neutrophil elastase with peptidyl electrophilic ketones. 2. Orally active p(G)-Val-Pro-Val pentafluoroethyl ketones
Angelastro,Baugh,Bey,Burkhart,Chen,Durham,Hare,Huber,Janusz,Koehl,Marquart,Mehdi,Peet
, p. 4538 - 4553 (2007/10/02)
Valylprolylvalyl pentafluoroethyl ketones with different N-protecting groups were evaluated in vitro and in vivo as inhibitors of human neutrophil elastase (HNE). Several of these compounds were found to be orally active in HNE-induced rat and hamster lun
