105089-65-4Relevant academic research and scientific papers
A new convenient procedure for the synthesis of pyrrolo[2,1-c][1,4] benzodiazepines
Courtney, Stephen M.,Thurston, David E.
, p. 5327 - 5328 (2007/10/02)
An efficient synthesis of the pyrrolo[2,1-c][1,4] (PBD) ring system based on a new cyclisation procedure is reported. The parent unsubstituted PBD (4a) and the benzyl derivative (4b) of the natural product DC-81 (4c) have been synthesized to illustrate the utility of this procedure.
A versatile and efficient synthesis of carbinolamine-containing pyrrolo[1,4]benzodiazepines via the cyclization of N-(2-aminobenzoy 1)pyrrolidine-2-carboxaldehyde diethyl thioacetals: Total synthesis of prothracarcin
Langley, David R.,Thurston, David E.
, p. 91 - 97 (2007/10/02)
A versatile and efficient synthesis of carbinolamine-containing pyrrolo[1,4]benzodiazepines (or the corresponding imine forms) of types 2, 7, and 8 is described that involves mercuric chloride mediated cyclization of the corresponding N-(2-aminobenzoyl)py
