1051315-79-7

Basic information

• Product Name: 4-(2-bromoethoxy)-7-methoxyquinoline
• Synonyms: 4-(2-bromoethoxy)-7-methoxyquinoline
• CAS NO: 1051315-79-7
• Molecular Weight: 282.137
• Mol File: 1051315-79-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(2-bromoethoxy)-7-methoxyquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-bromoethoxy)-7-methoxyquinoline(1051315-79-7)
• EPA Substance Registry System: 4-(2-bromoethoxy)-7-methoxyquinoline(1051315-79-7)

Safety Data

• Hazardous Substances Data: 1051315-79-7(Hazardous Substances Data)

Upstream product

• 82121-05-9 4-hydroxy-7-methoxyquinoline 
• 106-93-4 ethylene dibromide 

Relevant articles and documents

Acetylene-free synthesis of vinyloxy pyridine and quinoline

Copper-catalyzed vinylation of 2- and 4-hydroxy pyridine and quinoline affords exclusively N-vinylation products. However, vinyl ethers of 4-hydroxy pyridine and quinoline can be prepared via a three-step sequence involving copper-catalyzed C-O cross coupling reaction of the corresponding N-heteroaryl bromides with ethylene glycol, chlorination of the terminal alcohol, and dehydrohalogenation of the β-chloro ethers. Although not efficient in 2-hydroxy series, this method can be conveniently applied to the preparation of various aza-aryl vinyl ethers in moderate to good overall yields.