1051393-66-8

Basic information

• Product Name: (1R,2S,5S)-rel-3-[(tert-butoxy)carbonyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid
• Synonyms: (1R,2S,5S)-rel-3-[(tert-butoxy)carbonyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid;(1R,2S,5S)
• CAS NO: 1051393-66-8
• Molecular Formula: C11H17NO4
• Molecular Weight: 227.25698
• Mol File: 1051393-66-8.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 355.9±25.0 °C(Predicted)
• Appearance: /
• Density: 1.276±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.03±0.20(Predicted)
• CAS DataBase Reference: (1R,2S,5S)-rel-3-[(tert-butoxy)carbonyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,5S)-rel-3-[(tert-butoxy)carbonyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid(1051393-66-8)
• EPA Substance Registry System: (1R,2S,5S)-rel-3-[(tert-butoxy)carbonyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid(1051393-66-8)

Safety Data

• Hazardous Substances Data: 1051393-66-8(Hazardous Substances Data)

Usage

General Description

"(1R,2S,5S)-rel-3-[(tert-butoxy)carbonyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid" is a complex chemical compound with a bicyclic structure. It contains a carboxylic acid functional group and a tert-butoxy carbonyl group, and is a derivative of 3-azabicyclo[3.1.0]hexane-2-carboxylic acid. The stereochemistry of the compound is specified by the (1R,2S,5S) configuration, indicating the arrangement of substituents around the chiral centers. (1R,2S,5S)-rel-3-[(tert-butoxy)carbonyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid may have potential applications in pharmaceuticals, agrochemicals, or materials science, and its specific properties and uses would depend on further research and testing.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1051393-66-8 rac-cis(1S,2R,5R)-3-[(tert-butoxy)carbonyl]-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 
• 909037-18-9 3,7-dipropyl-7-aza-3-azoniabicyclo[3.3.1]nonane 
• 936551-50-7 tert-butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate 
• 124-38-9 carbon dioxide 
• 27762-08-9 trans-3-aza-bicyclo[3.1.0]hexane-2-carboxylic acid 
• 73836-88-1 3,4-methanoproline hydrochloride salt 
• 33294-81-4 (1R,2S,5S)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 
• 1051393-66-8 (trans)-3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 

Downstream Products

• 1017273-65-2 3-tert-butyl 2-methyl 3-azabicyclo[3.1.0]hexane-2,3-dicarboxylate 
• 937244-10-5 (+)-cis-(1S,2R,5R)-3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 
• 400720-05-0 (-)-trans-(1S,2S,5R)-3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 
• 167611-99-6 (-)-cis-(1R,2S,5S)-3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 
• 1051393-66-8 (+)-trans-(1R,2R,5S)-3-(tert-butoxycarbonyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 
• 1097132-93-8 (1S,2S,5R)-3-((R)-2-hydroxy-3,3-dimethylbutyryl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 5-chloro-2-tetrazol-1-ylbenzylamide 
• 1097132-95-0 (1S,2S,5R)-3-((R)-2-hydroxy-2-phenylacetyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 5-chloro-2-tetrazol-1-ylbenzylamide 
• 1097133-19-1 (1S,2S,5R)-3-((R)-2-hydroxy-4,4-dimethylpentanoyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 5-chloro-2-tetrazol-1-ylbenzylamide 
• 1097133-36-2 (1S,2S,5R)-3-((R)-2-hydroxy-3-phenylpropionyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 5-chloro-2-tetrazol-1-yl-benzylamide 
• 1097133-32-8 (1S,2S,5R)-3-((R)-2-cyclohexyl-2-hydroxyacetyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 5-chloro-2-tetrazol-1-ylbenzylamide 
• 1097133-21-5 (1S,2S,5R)-3-((R)-3-cyclopropyl-2-hydroxypropionyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 5-chloro-2-tetrazol-1-ylbenzylamide 
• 1097133-34-0 (1S,2S,5R)-3-((R)-3-tert-butoxy-2-hydroxypropionyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid 5-chloro-2-tetrazol-1-ylbenzylamide 

Relevant articles and documents

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The title compounds were synthesized by a 5-step facile transformation of the key intermediate 4, itself obtained by a 'one-pot' sulfone-mediated cyclopropanation from chiral synthon (R)-1 and (2R)-glycidyl triflate.

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