10514-70-2

Basic information

• Product Name: 2H-1,4-Benzoxazin-3(4H)-one, 2,2-dimethyl-
• CAS NO: 10514-70-2
• Molecular Formula: C10H11NO2
• Molecular Weight: 177.203
• Mol File: 10514-70-2.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: 2H-1,4-Benzoxazin-3(4H)-one, 2,2-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,4-Benzoxazin-3(4H)-one, 2,2-dimethyl-(10514-70-2)
• EPA Substance Registry System: 2H-1,4-Benzoxazin-3(4H)-one, 2,2-dimethyl-(10514-70-2)

Safety Data

• Hazardous Substances Data: 10514-70-2(Hazardous Substances Data)

Usage

General Description

2H-1,4-Benzoxazin-3(4H)-one, 2,2-dimethyl- is a chemical compound with the molecular formula C10H9NO2. It is a derivative of benzoxazinone and is commonly used in the agricultural sector as a natural defense chemical produced by plants. 2H-1,4-Benzoxazin-3(4H)-one, 2,2-dimethyl- has been found to possess antifungal, antibacterial, and insecticidal properties. It is also known to have potential applications in the pharmaceutical industry for its bioactive properties. Additionally, 2H-1,4-Benzoxazin-3(4H)-one, 2,2-dimethyl- has been studied for its potential role in plant protection against pests and diseases, making it an important compound in the field of plant biotechnology and crop protection.

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Downstream Products

• 866089-28-3 2,2-dimethyl-3,4-dihydro-2H-1,4-benzoxazine 

Relevant articles and documents

PYRROLOPYRROLE COMPOSITIONS AS PYRUVATE KINASE (PKR) ACTIVATORS

The disclosure relates to modulating pyruvate kinase and provides novel chemical compounds of formula (I) useful as activators of PKR, as well as various uses of these compounds. PKR activating compounds are useful in the treatment of diseases and disorders associated with PKR and/or PKM2, such as pyruvate kinase deficiency (PKD), sickle cell disease (SCD), and thalassemia.

Discovery of novel benzo[b][1,4]oxazin-3(4H)-ones as poly(ADP-ribose) polymerase inhibitors

Structure based drug design of a series of novel 1,4-benzoxazin-3-one derived PARP-1 inhibitors are described. The synthesis, enzymatic & cellular activities and pharmacodynamic effects are described. Optimized analogs demonstrated inhibition of poly-ADP-ribosylation in SW620 tumor bearing nude mice through 24 h following a single dose.

GLYCOSIDE DERIVATIVE AND USES THEREOF

This invention relates to compounds represented by formula (I) wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.