105141-61-5 Usage
Uses
Used in Pharmaceutical Industry:
2-Piperidinecarboxylic acid, 2-methyl-, (R)-(9CI) is used as a chiral building block for the synthesis of various compounds in the pharmaceutical industry. Its unique structure and properties make it a valuable component in the development of new drugs and pharmaceutical agents.
Used in Neurotransmitter Synthesis:
L-pipecolic acid is used as a key intermediate in the biosynthesis of the neurotransmitter γ-aminobutyric acid (GABA). GABA is an essential neurotransmitter that plays a crucial role in regulating neuronal excitability and has potential applications in the treatment of neurological disorders.
Used in Neurological Disorder Treatment:
2-Piperidinecarboxylic acid, 2-methyl-, (R)-(9CI) has been studied for its potential role in the treatment of neurological disorders. Its involvement in GABA synthesis suggests that it may have therapeutic potential in conditions related to imbalances in neurotransmitter levels, such as epilepsy, anxiety, and depression.
Used in Synthesis of Biologically Active Compounds:
L-pipecolic acid serves as a precursor for the synthesis of biologically active compounds. Its unique structure and properties make it a valuable starting material for the development of new compounds with potential applications in various fields, including medicine, agriculture, and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 105141-61-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,1,4 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 105141-61:
(8*1)+(7*0)+(6*5)+(5*1)+(4*4)+(3*1)+(2*6)+(1*1)=75
75 % 10 = 5
So 105141-61-5 is a valid CAS Registry Number.
105141-61-5Relevant academic research and scientific papers
An efficient, asymmetric synthesis of pipecolic acid and 2-alkyl pipecolic acids
Hou, Duen-Ren,Hung, Shin-Yi,Hu, Chung-Cheng
, p. 3858 - 3864 (2007/10/03)
Both (R)- and (S)-pipecolic acids and their 2-alkyl derivatives have been synthesized via diastereoselective alkylations of (R)-5-phenylmorpholin-2-one 5.
Preparation and Use of Chloromethyl (-)-Menthyl Ether in the Synthesis of Optically Pure α-Branched α-Amino Nitriles
Shatzmiller, Shimon,Dolithzky, Ben-Zion,Bahar, Eliezer
, p. 375 - 379 (2007/10/02)
The synthesis of optically pure chloromethyl (-)-menthyl ether (2b) and its use in the synthesis of di-(-)-menthyl acetal (-)-menthyl (+)-menthyl acetals are described.The diastereomeric mixed acetals 7a,b and 8a,b are easily obtainable from the nitrones 5 and 6, KCN and 2b.The mixture of diastereomers are separated into the pure components 7a, 7b and 8a, 8b by simple silica gel column chromatography.Hydrolysis of these products (H2O2/Na2CO3, ultrasound) followed by N-O cleavage affords the heterocyclic α-methyl-α-amino amides 11a, 11b and 12a, 12b.These are subsequently hydrolyzed to give the corresponding α-methyl-α-amino acids with S and R configuration, respectively.
