105166-41-4

Basic information

• Product Name: N-benzyl-6,7,8,9-tetrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxamide
• Synonyms: N-benzyl-6,7,8,9-tetrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxamide
• CAS NO: 105166-41-4
• Molecular Weight: 337.419
• Mol File: 105166-41-4.mol

Chemical Properties

• CAS DataBase Reference: N-benzyl-6,7,8,9-tetrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-6,7,8,9-tetrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxamide(105166-41-4)
• EPA Substance Registry System: N-benzyl-6,7,8,9-tetrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxamide(105166-41-4)

Safety Data

• Hazardous Substances Data: 105166-41-4(Hazardous Substances Data)

Upstream product

• 105166-36-7 diethyl 2-(3-methoxyphenyl)-2-methylhexanedioate 
• 105166-37-8 1-ethyl hydrogen 2-(3-methoxyphenyl)-2-methylhexanedioate 
• 105166-39-0 5-Chlorocarbonyl-2-(3-methoxy-phenyl)-2-methyl-pentanoic acid ethyl ester 
• 105166-35-6 2-(3-methoxyphenyl)propanoic acid ethyl ester 
• 1798-09-0 m-methoxyphenylacetic acid 
• 35553-92-5 ETHYL 3-METHOXYPHENYLACETATE 
• 105166-40-3 6,7,8,9-tetrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxylic acid 
• 100-46-9 benzylamine 
• 105166-38-9 5,6,7,8-tetrahydro-3-methoxy-5-methyl-5,8-methano-5H-benzocycloheptene-9,10(8H)-dione 

Downstream Products

• 105166-45-8 3-benzyl-2,3,4,5-tetrahydro-1-methyl-1,4-ethano-1H-3-benzazepin-8-ol 
• 105166-46-9 3-benzyl-2,3,4,5-tetrahydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepine 
• 105166-44-7 3-benzyl-4,5-dihydro-8-hydroxy-1-methyl-1,4-ethano-1H-3-benzazepin-2(3H)-one 
• 105166-48-1 3-benzyl-3,4-dihydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepin-5(2H)-one 
• 105166-47-0 3-benzyl-2,3,4,5-tetrahydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepin-5-ol 
• 105985-24-8 3-benzyl-4,5-dihydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepin-2(3H)-one 
• 105186-64-9 3-benzyl-3,4-dihydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepine-2,5-dione 
• 105166-42-5 N-benzyl-8-bromo-6,7,8,9-tetrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxamide 
• 105166-43-6 2-Bromo-3-methoxy-5-methyl-9-oxo-6,7,8,9-tetrahydro-5H-benzocycloheptene-5-carboxylic acid benzylamide 

Relevant articles and documents

Bridged-ring Nitrogen Compounds. Part 7. Synthesis of the 1,4-Ethano-3-benzazepine Ring System

9-Bromobenzosuberone was converted via 9-cyanobenzosuberone into several other 9-substituted benzosuberones, but attemps to cause them to cyclise to the tricyclic 1,4-ethano-3-benzazepine ring system were unsuccessful.Both ethyl phenylacetate and ethyl 3-methoxyphenylacetate were converted by conventional procedures into the corresponding 6,7,8,9-tetrahydro-5-methyl-9,10-dioxo-5,8-methano-5H-benzocycloheptenes.The 3-methoxy derivative was further converted into N-benzyl-8-bromo-6,7,8,9-tertrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxamide which could be converted into the tricyclic 3-benzyl-2,3,4,5-tetrahydro-8-methoxy-1-methyl-2,5-dioxo-1,4-ethano-1H-3-benzazepine and thence in two steps into both 3-benzyl-2,3,4,5-tetrahydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepine and 3-benzyl-2,3,4,5-tetrahydro-8-hydroxy-1-methyl-1,4-ethano-1H-3-benzazepine.Also prepared were 3-benzyl-2,3,4,5-tetrahydro-5-hydroxy-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepine and 3-benzyl-3,4-dihydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepin-5(2H)-one.