105985-24-8

Basic information

• Product Name: 3-benzyl-4,5-dihydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepin-2(3H)-one
• Synonyms: 3-benzyl-4,5-dihydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepin-2(3H)-one
• CAS NO: 105985-24-8
• Molecular Weight: 321.419
• Mol File: 105985-24-8.mol

Chemical Properties

• CAS DataBase Reference: 3-benzyl-4,5-dihydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepin-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-4,5-dihydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepin-2(3H)-one(105985-24-8)
• EPA Substance Registry System: 3-benzyl-4,5-dihydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepin-2(3H)-one(105985-24-8)

Safety Data

• Hazardous Substances Data: 105985-24-8(Hazardous Substances Data)

Upstream product

• 105166-35-6 2-(3-methoxyphenyl)propanoic acid ethyl ester 
• 105166-40-3 6,7,8,9-tetrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxylic acid 
• 100-46-9 benzylamine 
• 105166-42-5 N-benzyl-8-bromo-6,7,8,9-tetrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxamide 
• 105186-64-9 3-benzyl-3,4-dihydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepine-2,5-dione 
• 105166-41-4 N-benzyl-6,7,8,9-tetrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxamide 
• 105166-36-7 diethyl 2-(3-methoxyphenyl)-2-methylhexanedioate 
• 105166-37-8 1-ethyl hydrogen 2-(3-methoxyphenyl)-2-methylhexanedioate 
• 105166-39-0 5-Chlorocarbonyl-2-(3-methoxy-phenyl)-2-methyl-pentanoic acid ethyl ester 
• 105166-38-9 5,6,7,8-tetrahydro-3-methoxy-5-methyl-5,8-methano-5H-benzocycloheptene-9,10(8H)-dione 
• 1798-09-0 m-methoxyphenylacetic acid 
• 35553-92-5 ETHYL 3-METHOXYPHENYLACETATE 
• 105166-44-7 3-benzyl-4,5-dihydro-8-hydroxy-1-methyl-1,4-ethano-1H-3-benzazepin-2(3H)-one 
• 74-88-4 methyl iodide 

Downstream Products

• 105166-46-9 3-benzyl-2,3,4,5-tetrahydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepine 

Relevant articles and documents

Bridged-ring Nitrogen Compounds. Part 7. Synthesis of the 1,4-Ethano-3-benzazepine Ring System

9-Bromobenzosuberone was converted via 9-cyanobenzosuberone into several other 9-substituted benzosuberones, but attemps to cause them to cyclise to the tricyclic 1,4-ethano-3-benzazepine ring system were unsuccessful.Both ethyl phenylacetate and ethyl 3-methoxyphenylacetate were converted by conventional procedures into the corresponding 6,7,8,9-tetrahydro-5-methyl-9,10-dioxo-5,8-methano-5H-benzocycloheptenes.The 3-methoxy derivative was further converted into N-benzyl-8-bromo-6,7,8,9-tertrahydro-3-methoxy-5-methyl-9-oxo-5H-benzocycloheptene-5-carboxamide which could be converted into the tricyclic 3-benzyl-2,3,4,5-tetrahydro-8-methoxy-1-methyl-2,5-dioxo-1,4-ethano-1H-3-benzazepine and thence in two steps into both 3-benzyl-2,3,4,5-tetrahydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepine and 3-benzyl-2,3,4,5-tetrahydro-8-hydroxy-1-methyl-1,4-ethano-1H-3-benzazepine.Also prepared were 3-benzyl-2,3,4,5-tetrahydro-5-hydroxy-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepine and 3-benzyl-3,4-dihydro-8-methoxy-1-methyl-1,4-ethano-1H-3-benzazepin-5(2H)-one.