105168-93-2

Upstream product

• 75-30-9 2-iodo-propane 
• 121-88-0 5-Nitro-2-aminophenol 
• 75-26-3 isopropyl bromide 

Downstream Products

• 80259-11-6 2-isopropoxy-4-nitroacetanilide 
• 105168-98-7 (1,1-Dioxo-1H-1λ⁶-benzo[d]isothiazol-3-yl)-(2-isopropoxy-4-nitro-phenyl)-amine 
• 169211-11-4 N-(2-isopropyloxy-4-nitrophenyl)methanesulfonamide 
• 192934-86-4 N-methyl-2-isopropoxy-4-nitroaniline 
• 105169-09-3 N-(4-Amino-2-isopropoxy-phenyl)-acetamide 
• 105169-15-1 N⁴-(1,1-Dioxo-1H-1λ⁶-benzo[d]isothiazol-3-yl)-2-isopropoxy-benzene-1,4-diamine 
• 105169-03-7 N¹-(1,1-Dioxo-1H-1λ⁶-benzo[d]isothiazol-3-yl)-2-isopropoxy-benzene-1,4-diamine 
• 105169-12-8 N-[4-(1,1-Dioxo-1H-1λ⁶-benzo[d]isothiazol-3-ylamino)-2-isopropoxy-phenyl]-acetamide 
• 105169-19-5 C₂₁H₂₃N₅O₇S 
• 105169-23-1 C₂₁H₂₃N₅O₇S 
• 1251863-51-0 C₉H₁₁IN₂O₃ 
• 1251863-52-1 C₉H₁₀INO₃ 
• 1251863-53-2 C₉H₁₂INO 

Relevant academic research and scientific papers

IMIDAZO [1,2-A]PYRIDINE DERIVATIVES AS FGFR KINASE INHIBITORS FOR USE IN THERAPY

The invention relates to new bicyclic heterocyclyl derivatives of formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Synthesis of carbon-11 labeled sulfonanilide analogues as new potential PET agents for imaging of aromatase in breast cancer

Aromatase is a particularly good target in the treatment of estrogen receptor positive breast cancer. Novel carbon-11 labeled sulfonanilide analogues, N-[11C]methyl-N-(2-alkyloxy-4-nitrophenyl)-methanesulfonamide s ([11C]3a-f, alkyl

SULFONANILIDE ANALOGS AS SELECTIVE AROMATASE MODULATORS

Compounds and methods suppressing aromatase activity expression in cancer cells. Provided are compounds are those of formula I: wherein R1 may be alkyl, cycloakyl, haloalkyl, aryl, substituted aryl, haloaryl, alkoxy, alkylaryl, and arylalkyl; R2 is H, alk

Novel sulfonanilide analogues suppress aromatase expression and activity in breast cancer cells independent of COX-2 inhibition

Aromatase is a particularly attractive target in the treatment of estrogen receptor positive breast cancer. Aromatase levels in breast cancer cells are enhanced by prostaglandins and reduced by COX inhibitors. The synthesis and biological evaluation of a

Quinone Imine Route to Benzimidazol-2-ylcarbamates. Part 3. Effect of Extension of Conjugation in the Quinone Imine.

5-Aminobenzimidazol-2-ylcarbamates (11) and (17), in which the amine is linked to position 3 of 1,2-benzisothiazole 1,1-dioxide have been synthesised in good yields from the guanidines (10) and (16) by oxidative cyclisation.The cyclisation is regiospecific.It is likely that quinone imines with extended conjugation are intermediates in this reaction.