169211-11-4Relevant articles and documents
New nimesulide derivatives with amide/sulfonamide moieties: Selective COX-2 inhibition and antitumor effects
Güng?r, Tu?ba,Ozleyen, Adem,Y?lmaz, Yakup Berkay,Siyah, Pinar,Ay, Mehmet,Durda??, Serdar,Tumer, Tugba Boyunegmez
, (2021)
Seventeen new amide/sulfonamide containing nimesulide derivatives were synthesized and characterized by several spectroscopic techniques and primarily investigated for their inhibitory potential on COX enzymes and other pro-inflammatory factors. Experimen
Synthesis of carbon-11 labeled sulfonanilide analogues as new potential PET agents for imaging of aromatase in breast cancer
Wang, Min,Lacy, Gabrielle,Gao, Mingzhang,Miller, Kathy D.,Sledge, George W.,Zheng, Qi-Huang
, p. 332 - 336 (2007/10/03)
Aromatase is a particularly good target in the treatment of estrogen receptor positive breast cancer. Novel carbon-11 labeled sulfonanilide analogues, N-[11C]methyl-N-(2-alkyloxy-4-nitrophenyl)-methanesulfonamide s ([11C]3a-f, alkyl
SULFONANILIDE ANALOGS AS SELECTIVE AROMATASE MODULATORS
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Page/Page column title page; 19; 1/15, (2010/11/28)
Compounds and methods suppressing aromatase activity expression in cancer cells. Provided are compounds are those of formula I: wherein R1 may be alkyl, cycloakyl, haloalkyl, aryl, substituted aryl, haloaryl, alkoxy, alkylaryl, and arylalkyl; R2 is H, alk
Novel sulfonanilide analogues suppress aromatase expression and activity in breast cancer cells independent of COX-2 inhibition
Su, Bin,Diaz-Cruz, Edgar S.,Landini, Serena,Brueggemeier, Robert W.
, p. 1413 - 1419 (2007/10/03)
Aromatase is a particularly attractive target in the treatment of estrogen receptor positive breast cancer. Aromatase levels in breast cancer cells are enhanced by prostaglandins and reduced by COX inhibitors. The synthesis and biological evaluation of a
