105198-75-2Relevant academic research and scientific papers
Synthesis, cannabinoid receptor activity, and enzymatic stability of reversed amide derivatives of arachidonoyl ethanolamide
Parkkari, Teija,Savinainen, Juha R.,Raitio, Katri H.,Saario, Susanna M.,Matilainen, Laura,Sirvioe, Tuomas,Laitinen, Jarmo T.,Nevalainen, Tapio,Niemi, Riku,Jaervinen, Tomi
, p. 5252 - 5258 (2007/10/03)
Retroanandamide (2f) and its 10 analogues (1a-e, 2a-e) were synthesized and evaluated for the cannabinoid receptor activation by a [35S]GTPγS binding assay using rat cerebellar membranes, and Chinese hamster ovary cell membranes expressing huma
Tandem reduction-olefination of triethyl 2-acyl-2-fluoro-2-phosphonoacetates and a synthetic approach to Cbz-Gly-Ψ[(Z)-CF{double bond, long}C]-Gly dipeptide isostere
Sano, Shigeki,Kuroda, Yoko,Saito, Katsuyuki,Ose, Yukiko,Nagao, Yoshimitsu
, p. 11881 - 11890 (2007/10/03)
(Z)-α-Fluoro-α,β-unsaturated esters (Z)-7a-f were stereoselectively prepared by a tandem reduction-olefination of triethyl 2-acyl-2-fluoro-2-phosphonoacetates 6a-f with NaBH4 in EtOH. A concise synthesis of Cbz-Gly-Ψ[(Z)-CF{double bond, long}C]-Gly (26) as a dipeptide isostere was achieved via the tandem reduction-olefination of the corresponding 2-acyl-2-fluoro-2-phosphonoacetate 20.
Bruchins - Mitogenic 3-(hydroxypropanoyl) esters of long chain diols from weevils of the bruchidae
Oliver, James E,Doss, Robert P,Williamson, R.Thomas,Carney, John R,DeVilbiss, E.David
, p. 7633 - 7641 (2007/10/03)
Mono- and bis 3-(hydroxypropanoyl) esters of long chain, unsaturated diols have been isolated and identified from two genera of the family Bruchidae, and have been shown to be responsible for the mitogenic activity observed on pea pods resulting from oviposition by the pea weevil, Bruchus pisorum. The mitogenic compounds have been characterized and synthesized.
A General Strategy for the Synthesis of Monohydroxyeicosatetraenoic Acids: Total Synthesis of 5(S)-Hydroxy-6(E),8,11,14(Z)-eicosatetraenoic Acid (5-HETE) and 12(S)-Hydroxy-5,8,14(Z),10(E)-eicosatetraenoic Acid (12-HETE)
Nicolaou, K. C.,Ladduwahetty, T.,Taffer, I. M.,Zipkin, R. E.
, p. 344 - 347 (2007/10/02)
Stereocontrolled total syntheses of 5(S)-hydroxy-6(E),8,11,14(Z)-eicosatetraenoic acid (5-HETE) and 12(S)-hydroxy-5,8,14(Z),10(E)-eicosatetraenoic acid (12-HETE) via palladium(0)-copper(I) coupling technology are described.
