310409-17-7Relevant articles and documents
Ruthenium-Catalyzed Oxidative Cleavage of Alkynes to Carboxylic Acids
Yang, Dan,Chen, Fei,Dong, Ze-Min,Zhang, Dan-Wei
, p. 2221 - 2223 (2004)
We describe an efficient method for the oxidative cleavage of alkynes to carboxylic acids using a combination of RuO2/Oxone/NaHCO3 in a CH3CN/H2O/EtOAc solvent system. Both internal and terminal alkynes, regardless of their electron density, can be oxidized to carboxylic acids in excellent yield (up to 99%). 1H NMR spectroscopy and ESI-MS experiments provided evidence for α-diketones and anhydrides as possible intermediates in these oxidation reactions.
Fullerene derivatives as dual inhibitors of HIV-1 reverse transcriptase and protease
Yasuno, Takumi,Ohe, Tomoyuki,Kataoka, Hiroki,Hashimoto, Kosho,Ishikawa, Yumiko,Furukawa, Keigo,Tateishi, Yasuhiro,Kobayashi, Toi,Takahashi, Kyoko,Nakamura, Shigeo,Mashino, Tadahiko
, (2020/11/20)
In the present study, we newly synthesized three types of novel fullerene derivatives: pyridinium-type derivatives trans-3a and 4a-5b, piperidinium-type derivative 9, and proline-type derivatives 10a-12. Among the assessed compounds, 5a, 10e, 10f, 10i, 11
Synthesis of deuterated isopentyl pyrophosphates for chemo-enzymatic labelling methods: GC-EI-MS based 1,2-hydride shift in epicedrol biosynthesis
Said, Madhukar S.,Navale, Govinda R.,Gajbhiye, Jayant M.,Shinde, Sandip S.
, p. 28258 - 28261 (2019/09/30)
A sesquiterpene epicedrol cyclase mechanism was elucidated based on the gas chromatography coupled to electron impact mass spectrometry fragmentation data of deuterated (2H) epicedrol analogues. The chemo-enzymatic method was applied for the specific synthesis of 8-position labelled farnesyl pyrophosphate and epicedrol. EI-MS fragmentation ions compared with non-labelled and isotopic mass shift fragments suggest that the 2H of C6 migrates to the C7 position during the cyclization mechanism.