10520-95-3

Upstream product

• 2088-71-3 testosterone benzoate 
• 64-19-7 acetic acid 
• 141-78-6 ethyl acetate 

Downstream Products

• 71996-13-9 17β-benzoyloxy-4-oxa-androst-5-en-3-one 
• 85198-46-5 17β-benzoyloxy-4-thia-5-androsten-3-one 
• 87126-24-7 4-thia-androsten-3,17-diol 17-benzoate 
• 87126-26-9 5-benzyloxy-4-oxa-5ξ-androstan-17β-ol 

Relevant academic research and scientific papers

Directing Group in Decarboxylative Cross-Coupling: Copper-Catalyzed Site-Selective C-N Bond Formation from Nonactivated Aliphatic Carboxylic Acids

Copper-catalyzed directed decarboxylative amination of nonactivated aliphatic carboxylic acids is described. This intramolecular C-N bond formation reaction provides efficient access to the synthesis of pyrrolidine and piperidine derivatives as well as the modification of complex natural products. Moreover, this reaction presents excellent site-selectivity in the C-N bond formation step through the use of directing group. Our work can be considered as a big step toward controllable radical decarboxylative carbon-heteroatom cross-coupling.