105214-34-4Relevant academic research and scientific papers
Extension of a one-pot synthesis of bicyclo[n.4.0]alkanols; indications of scope and limitations for formation of substituted bicyclo[n.4.0]alkanols
Loughlin, Wendy A.,McCleary, Michelle A.
, p. 761 - 770 (2005)
Novel bicyclo[n,2.0]alkan-1-ols with incorporation of methyl substitution at the C6 bridgehead and C2 position on a six-member ring, and incorporation of methyl substitution at the C2 position on a five-member ring were obtained. The presence or absence of a group at these positions had a role in the preference of the major stereochemical isomer observed. Potential limitations of the cyclisation methodology was observed when the ketone was hindered (camphor), and where conjugation was present in the enolate. By contrast, another functional group, as illustrated with 1,4-cyclohexanedione mono-ethylene ketal 24, can be incorporated in the bicyclo[4.2.0]octan-1-ol, and the ketal group converted to a ketone, as in 28, without disrupting the bicyclo[4.2.0]octan-1-ol ring.
Carbenoid Anion Behavior of Dilithio Derivatives of Thioacetal Alcohols. Stereochemistry and Mechanism of Ring Closures by Oxyanion-Facilitated CH Bond Insertion
Ritter, Robert H.,Cohen, Theodore
, p. 3718 - 3725 (2007/10/02)
Like other lithio derivatives of thioacetals bearing a second anionic site, dilithio derivatives of 3,3-, 5,5-, and 6,6-bis(phenylthio) alcohols decompose at or below ambient temperature to yield products ascribable to carbenoid intermediates.The 5,5-deri
ALKYLATION OF SILYL ENOL ETHERS WITH PUMMERER GENERATED VINYL THIONIUM IONS
Hunter, Roger,Simon, Clive D.
, p. 1385 - 1386 (2007/10/02)
Silyl enol ethers (1,2) are γ-alkylated in moderate yields by a series of vinyl thionium ions generated from the corresponding allylic sulphoxides (3-6) with TMSOTf and diisopropylethylamine in CH2Cl2 at -78 deg C
