105273-33-4

Basic information

• Product Name: 1-chloro-2-(trimethylsilylethynyl)benzene
• Synonyms: 1-chloro-2-(trimethylsilylethynyl)benzene
• CAS NO: 105273-33-4
• Molecular Weight: 208.763
• Mol File: 105273-33-4.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1-chloro-2-(trimethylsilylethynyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-2-(trimethylsilylethynyl)benzene(105273-33-4)
• EPA Substance Registry System: 1-chloro-2-(trimethylsilylethynyl)benzene(105273-33-4)

Safety Data

• Hazardous Substances Data: 105273-33-4(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 873-31-4 2-chlorophenylacetylene 
• 1066-54-2 trimethylsilylacetylene 
• 996-50-9 N,N-diethyl-1,1,1-trimethylsilanamine 
• 105273-35-6 1,1,2,2-Tetrafluoro-2-(1,1,2,2-tetrafluoro-ethoxy)-ethanesulfonic acid 2-chloro-phenyl ester 
• 615-41-8 2-iodochlorobenzene 
• 694-80-4 2-bromo-1-chlorobenzene 

Downstream Products

• 7517-81-9 methyl 3-(2-chlorophenyl)propiolate 
• 136612-84-5 (E)-1,4-bis(2-chlorophenyl)but-1-en-3-yne 
• 80221-17-6 1,4-bis(o-chlorophenyl)buta-1,3-diyne 
• 767-91-9 1-ethynyl-2-methoxybenzene 
• 130654-91-0 3,3,3-trifluoro-1-(2-methoxyphenyl)propan-1-one 
• 1250432-16-6 1-(2-chlorophenyl)-3,3,3-trifluoropropan-1-one 
• 130654-80-7 1-methoxy-2-(3,3,3-trifluoroprop-1-yn-1-yl)benzene 
• 122247-01-2 1-chloro-2-(3,3,3-trifluoroprop-1-yn-1-yl)benzene 
• 1401250-41-6 C₁₄H₉Cl₂N₃ 
• 1401250-38-1 C₁₄H₉Cl₂N₃ 
• 1373551-00-8 C₁₇H₂₆BClO₂Si 

Relevant articles and documents

Microwave-assisted copper- and palladium-catalyzed sonogashira-type coupling of aryl bromides and iodides with trimethylsilylacetylene

An efficient and rapid method was developed for the synthesis of 1-aryl-2-(trimethylsilyl)acetylene. Copper and palladium-catalyzed sonogashira-type coupling of trimethylsilylacetylene and aryl bromides or iodides in the presence of triethylamine as base

Asymmetric Hydrosilylation of β-Silyl Styrenes Catalyzed by a Chiral Palladium Complex

A palladium complex coordinated with a chiral SIPHOS ligand was evaluated as an efficient catalyst for asymmetric hydrosilylation of β-silyl styrenes with trichlorosilane and 23 1,2-bis(silyl) chiral compounds were produced. Good to excellent enantioselec

Regioselective Gold-Catalyzed Hydration of CF3- and SF5-alkynes

The regioselective gold-catalyzed hydration of CF3- and SF5-alkynes is described. The corresponding trifluoromethylated and pentasulfanylated ketones are obtained in up to 91% yield as single regioisomers showcasing the use of CF3 and SF5 as highly efficient directing groups in this reaction. Notably, this transformation represents the first use of CF3- and SF5-alkynes in gold catalysis.