105297-10-7

Basic information

• Product Name: 4-(4-AMINOPHENYL)THIOMORPHOLINE 1,1-DIOXIDE
• Synonyms: 4-THIOMORPHOLINOANILINE 1',1'-DIOXIDE;4-(4-AMINOPHENYL)THIOMORPHOLINE 1,1-DIOXIDE;4-(1,1-DIOXOTHIOMORPHOLINO)ANILINE;4-(1,1-DIOXO-1-THIOMORPHOLIN-4-YL)-PHENYLAMINE;4-(1,1-DIOXO-1LAMBDA*6*-THIOMORPHOLIN-4-YL)PHENYLAMINE;4-(4-AMINOPHENYL)-THIOMORPHOLINE 1,1-DIOXIDE EP;4-(1,1-Dioxidothiomorpholin-4-yl)aniline;4-(1,1-Dioxothiomorpholino)aniline 4-Thiomorpholinoaniline 1',1'-Dioxide
• CAS NO: 105297-10-7
• Molecular Formula: C₁₀H₁₄N₂O₂S
• Molecular Weight: 226.3
• Mol File: 105297-10-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 192.0 to 197.0 °C
• Boiling Point: 525.4°Cat760mmHg
• Flash Point: 271.6°C
• Appearance: /
• Density: 1.326g/cm³
• Vapor Pressure: 3.92E-11mmHg at 25°C
• Refractive Index: 1.615
• CAS DataBase Reference: 4-(4-AMINOPHENYL)THIOMORPHOLINE 1,1-DIOXIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-AMINOPHENYL)THIOMORPHOLINE 1,1-DIOXIDE(105297-10-7)
• EPA Substance Registry System: 4-(4-AMINOPHENYL)THIOMORPHOLINE 1,1-DIOXIDE(105297-10-7)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 105297-10-7(Hazardous Substances Data)

Usage

Description

4-(4-Aminophenyl)thiomorpholine 1,1-dioxide is a complex chemical compound belonging to the sulfonamide class, characterized by a unique structure that includes a four-membered heterocyclic ring, a phenyl ring, and various functional groups. These structural features contribute to its chemical reactivity, stability, and potential bioactivity, making it a versatile molecule for scientific research and industrial applications.

Uses

Used in Pharmaceutical Industry:
4-(4-Aminophenyl)thiomorpholine 1,1-dioxide is used as an intermediate in the synthesis of pharmaceutical compounds for its potential to contribute to the development of new drugs. Its unique structure and functional groups may offer specific properties that can be harnessed in medicinal chemistry to create therapeutic agents.
Used in Chemical Research:
In the field of chemical research, 4-(4-Aminophenyl)thiomorpholine 1,1-dioxide serves as a valuable compound for studying its reactivity and stability. Researchers can explore its interactions with other molecules and its potential applications in the synthesis of more complex chemical entities.
Used in Industrial Applications:
4-(4-Aminophenyl)thiomorpholine 1,1-dioxide is utilized in various industrial processes, where its unique structural features and chemical properties can be applied to develop new materials or improve existing ones. Its use in these applications may depend on factors such as cost-effectiveness, ease of synthesis, and compatibility with other materials.

InChI:InChI=1/C10H14N2O2S/c11-9-1-3-10(4-2-9)12-5-7-15(13,14)8-6-12/h1-4H,5-8,11H2

Upstream product

• 350-46-9 4-Fluoronitrobenzene 
• 90254-22-1 4-(p-nitrophenyl)-tetrahydro-4H-1,4-thiazine 
• 100-00-5 4-chlorobenzonitrile 
• 329943-64-8 4-(4-nitrophenyl)thiomorpholine 1,1-dioxide 

Downstream Products

• 1029802-58-1 N-(4-(1,1-dioxo-1λ⁶-thiomorpholin-4-yl)phenyl)-2-oxo-2-(2-phenylindolizin-3-yl)acetamide 
• 1403817-46-8 4-(4-((5-(thiophen-3-yl)-1H-pyrazolo[4,3-d]pyrimidin-7-yl)amino)phenyl)thiomorpholine 1,1-dioxide 
• 1403817-40-2 4-(4-((5-(thiophen-2-yl)-1H-pyrazolo[4,3-d]pyrimidin-7-yl)amino)phenyl)thiomorpholine1,1-dioxide 
• 1403817-72-0 4-(4-((5-(4-methoxyphenyl)-1H-pyrazolo[4,3-d]pyrimidin-7-yl)amino)phenyl)thiomorpholine 1,1-dioxide 
• 1403886-02-1 [4-(1,1-dioxo-1λ-6-thiomorpholin-4-yl)-phenyl]-(8-methoxy-3H-pyrazolo[3,4-c]quinolin-4-yl)-amine 

Relevant articles and documents

COMPOUNDS AND THEIR USES AS SPLEEN TYROSINE KINASE INHIBITORS

Provided are compounds of Formula (I) which can be used as Syk inhibitors and potently as therapeutic agents against diseases mediated by Syk.

2, 4 -DIAMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS

The present invention relates to novel pyrimide derivatives of formula (I): that are useful as kinase inhibitors. More particularly, the present invention relates to novel pyrimidine compounds, methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment of proliferative disorders.