10534-89-1

Basic information

• Product Name: HEXAAMMINECOBALT(III) CHLORIDE
• Synonyms: HEXAAMINE COBALT(III) CHLORIDE;HEXAAMMINECOBALT(3) CHLORIDE;HEXAAMMINECOBALT(III) CHLORIDE;HEXAAMMINECOBALT TRICHLORIDE;HEXAMINECOBALT (III) CHLORIDE;HEXAMINOCOBALTIC CHLORIDE;HEXAMMINECOBALTIC CHLORIDE;HEXAMMINECOBALT(III) CHLORIDE
• CAS NO: 10534-89-1
• Molecular Formula: Cl3CoH18N6
• Molecular Weight: 267.48
• EINECS: 234-103-9
• Product Categories: Inorganics;Classes of Metal Compounds;Co (Cobalt) Compounds;Transition Metal Compounds;metal-ammine complexes
• Mol File: 10534-89-1.mol
• Article Data: 9

Chemical Properties

• Melting Point: 217 °C(lit.)
• Appearance: Orange to orange-brown/Powder
• Density: 1.71 g/mL at 25 °C(lit.)
• Storage Temp.: 2-8°C
• Solubility: Soluble in ammonia.
• Water Solubility: Soluble in ammonia and water.
• Stability: Stable. Incompatible with strong oxidizing agents.
• Merck: 14,4675
• CAS DataBase Reference: HEXAAMMINECOBALT(III) CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: HEXAAMMINECOBALT(III) CHLORIDE(10534-89-1)
• EPA Substance Registry System: HEXAAMMINECOBALT(III) CHLORIDE(10534-89-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• RIDADR: UN 2811 6.1/PG III
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 10534-89-1(Hazardous Substances Data)

Usage

Chemical Properties

solid

Uses

Different sources of media describe the Uses of 10534-89-1 differently. You can refer to the following data:
1. As reagent for pyrophosphoric acid, for the estimation of phosphate.
2. Hexaamminecobalt(III) chloride is a component of structural biology methods, especially for DNA or RNA, where the positive ions stabilize the tertiary structure of the phosphate backbone, which favors to solve their structure by X-ray crystallography. It serves as an excellent antibacterial and antiviral property.

Preparation

Synthesis of hexaamminecobalt(III) chloride2CoCl2+10NH3+2NH4Cl+H2O2 →2[Co(NH3) 6]Cl3+2H2OReaction. Dissolve 2.5 g (10.5 mmol) of cobalt(II) chloride hexahydrate and 1.7 g (32 mmol) of ammonium chloride (about 195% excess) in 15 mL of distilled water. Add 0.5 g of activated charcoal and 23 mL (380 mmol) of concentrated aqueous ammonia (about 624% excess). Cool the reaction mixture to 0 oC in an ice bath. Slowly add 2 mL (19.5 mmol) of 30% hydrogen peroxide (about 271% excess), with stirring – maintain the temperature below 10°C. After the hydrogen peroxide has been added, heat the reaction mixture to 60°C for about 30 minutes. Cool the reaction mixture to 0 oC to cause precipitation of the product.

General Description

Hexammine cobalt(III) is considered an analog of fully solvated magnesium, capable of activating some enzymes that requires magnesium. It is useful in DNA condensation studies.

Purification Methods

It crystallises from warm water (8mL/g) on cooling. [Bjerrum & McReynolds Inorg Synth II 217 1946.]

InChI:InChI=1/C6H12N4.ClH.Co/c1-7-2-9-4-8(1)5-10(3-7)6-9;;/h1-6H2;1H;/q;;+2/p-1

Upstream product

• 7647-01-0 hydrogenchloride 
• 7664-41-7 ammonia 
• 13859-51-3 pentaaminechlorocobalt(III) dichloride 
• 7646-79-9 cobalt(II) chloride 
• 10241-04-0 cobalt(III) chloride 
• 7440-48-4 cobalt 
• 7732-18-5 water 

Downstream Products

• 55448-50-5 α-trialaninecobalt(III) 
• 26079-87-8 {Colc3} 
• 15279-18-2 [Co(NH₃)6]⁽³⁺⁾*[Co(CO₃)3]^(3-)=[Co(NH₃)6][Co(CO₃)3] 
• 30364-77-3 α-triglycinecobalt(III) 

Related news

A study of the performance of hexaamminecobalt(III) chloride and tris(2,4-pentanediono)cobalt(III) as colouring materials for poly(vinyl chloride) and polystyrene08/11/2019

The compounds hexaamminecobalt(III) chloride and tris(2,4-pentanediono)cobalt(III) have been prepared. The compounds have octahedral structures. The initial decomposition temperature of the compounds has been obtained by thermogravimetry. The performance of the compounds as colouring materials f...detailed

Second-sphere coordination complex via hydrogen bonding: Synthesis, characterization, X-ray crystal structure determination and packing of hexaamminecobalt(III) chloride di(para-nitrobenzoate)08/09/2019

A reddish orange coloured crystalline solid of hexaamminecobalt(III) chloride di(para-nitrobenzoate) was obtained when hexaamminecobalt(III) chloride was reacted with the sodium salt of para-nitrobenzoic acid (1:3 molar ratio) in hot aqueous medium. This cobalt(III) complex salt has been charact...detailed

Role of second-sphere coordination in anion binding: Synthesis, characterization and X-ray structure of hexaamminecobalt(III) chloride hydrogen phthalate trihydrate and sodium hexaamminecobalt(III) benzoate monohydrate08/08/2019

In an effort to utilize [Co(NH3)6]3+cation as a new host for carboxylate ions, orange coloured crystalline solids of composition [Co(NH3)6]Cl(C8H5O4)2·3H2O (1) and Na[Co(NH3)6](C7H5O2)4·H2O (2) were obtained by reacting hot aqueous solutions of hexaamminecobalt(III) chloride with potassium hyd...detailed

Cationic cobaltammine as anion receptor: Synthesis, characterization, single crystal X-ray structure and packing analysis of hexaamminecobalt(III) chloride (R,R)-tartrate monohydrate08/06/2019

In an effort to utilize the [Co(NH3)6]3+ cation as a new anion receptor (binding agent) for dihydroxy dicarboxylate anion i.e., tartrate, orange single crystals of hexaamminecobalt(III) chloride (R,R)-tartrate monohydrate, [Co(NH3)6]Cl(C4H4O6)·H2O, were obtained by reacting hexaamminecobalt(III...detailed

Relevant articles and documents

Cationic cobaltammines as anion receptors: Synthesis and characterization of [Co(NH3)6](4-np)3.4H2O, [Co(NH3)6](2,4-dnp)3 and [Co(NH 3)6](2,4,6-tnp)3

In an effort to utilize [Co(NH3)6]3+ cation as a new host for mono-, di- and tri-substituted nitrophenolate anions, yellow solids of composition [Co(NH3)6](4-np) 3.4H2O, [Co(NH3)6](2,4-dnp) 3, and [Co(NH3)6](2,4,6-tnp)3 were obtained in high yields by reacting sodium salts of 4-np, 2,4-dnp and 2,4,6-tnp (where np=nitrophenolate, dnp=dinitrophenolate and tnp=trinitrophenolate,) with [Co(NH3)6]Cl3 respectively in 3:1 molar ratio in hot aqueous medium. These cobalt(III) complex salts have been characterized by elemental analyses and spectroscopic techniques (UV/Visible, IR and NMR). Single crystal X-ray structure determination of [Co(NH3) 6](4-np)3.4H2O revealed the presence of discrete ions, [Co(NH3)6]3+ and C 6H4NO3- in addition to four lattice water molecules in the solid state. A strong network of hydrogen bond interactions (N-H?O (phenolate), N-H?O (nitro), O-H?O (water) stabilize the crystal lattice. The formation of these salts and measurement of solubility products suggests that [Co(NH3) 6]3+ present in [Co(NH3)6]Cl 3 may be used as anion receptor for the nitrophenolate ions.

Role of second-sphere coordination in anion binding: Synthesis, characterization and X-ray structure of hexaamminecobalt(III) chloride hydrogen phthalate trihydrate and sodium hexaamminecobalt(III) benzoate monohydrate

In an effort to utilize [Co(NH3)6]3+cation as a new host for carboxylate ions, orange coloured crystalline solids of composition [Co(NH3)6]Cl(C8H5O 4)2·3H2O (1) and Na[Co(NH 3)6](C7H5O2) 4·H2O (2) were obtained by reacting hot aqueous solutions of hexaamminecobalt(III) chloride with potassium hydrogen phthalate and sodium benzoate in 1:3 molar ratio, respectively. The title complex salts were characterized by elemental analyses and spectroscopic studies (IR, UV/Visible and NMR). Single crystal X-ray structure determinations revealed the formation of second-sphere coordination complexes based on hydrogen bond interactions. In complex salt 1 only two out of three ionisable chloride ions present in [Co(NH3)6]Cl3 were replaced by two C8H5O4- ions whereas in complex salt 2 all the three ionisable chloride ions present in [Co(NH3)6]Cl3 were replaced and the final product was an adduct with another mole of sodium benzoate in solid state. The crystal lattice is stabilized by electrostatic forces of attraction and predominantly N-H?O interactions.

KINETICS AND PHOTOEFFECTS OF OXIDATION AND REDUCTION OF HEXAAMMINECOBALT COMPLEX IN ALKALINE MEDIA.

Cyclic voltammograms of hexaamminecobalt complex have been measured in high pH solutions. The spectroscopic result suggested that hydroxoamminecobalt complex adsorbed on the electrode surface during cathodic polarization, and this species grew to form cobalt hydroxide after a long time of electrolysis. Based on these results, the reaction mechanism is discussed. The effect of light on the electrode process has been studied by irradiating with ultraviolet light of the 254 nm mercury resonance line. It is indicated that the hydroxoammine complex is decomposed to cobalt hydroxide and free ligand under light.

Influence of the metal centers on the pKa of the pyrrole hydrogen of imidazole complexes of (NH3)5M3+, M(III) = Co(III), Rh(III), Ir(III), Ru(III)

The pKa's at 298 K, μ = 0.10 (NaCl), and the temperature dependence (273-343 K) for the deprotonation of the pyrrole NH of several imidazoles coordinated to (NH3)5M3+ moieties (M = CoIII, RhIII, IrIII, RuIII) are reported. A greater importance of dn configuration over ion size is found. Data summarized for various systems are as follows (ligand, M (pK298, ΔHa° in kcal/mol, ΔSa° in eu)): imidazole = imH, CoIII (9.99, 14.0 ± 0.5, 1.3 ± 1.6), RhIII (9.97, 13.6 ± 0.3, 0.1 ± 1.3), IrIII (10.05, 13.4 ± 0.3, 1.2 ± 1.0), RuIII (8.9, 10.0 ± 0.8, 3.7 ± 1.2); 2-methylimidazole = 2-MeimH, CoIII (10.67, 17.8 ± 0.7, 11.2 ± 2.4); 2,4(5)-dimethylimidazole = 2,5-Me2imH, CoIII (11.04, 13.4 ± 0.5, 5.3 ± 1.6), RuIII (10.20, 13.2 ± 0.6, -2.1 ± 1.6). 1H NMR spectra of low-spin d6 complexes of imidazoles and ring-methylated imidazoles are discussed for CoIII, RhIII, IrIII, and RuIII. C-2 and remote ring, C-5, substituents are shifted downfield relative to the free imidazole ligand in the order H+ > CoIII > RhIII > IrIII. The C-4 position is influenced competitively by σ-withdrawal ring substituents and TIP effects for CoIII. Assignments of the remote isomer for (NH3)5M(2,5-Me2imH)3+ (M = CoIII, RuIII) are made from the 1H NMR spectra of the CoIII and RuII complexes. The RuIII complexes of 2,5-Me2imH and the imidazolate form (2,5-Me2im-) both exhibit LMCT spectra. The imidazolato form has three bands at 655, 377, and 272 nm, proposed for II1 → IId, II2 → IId, and n → IId transitions, where II1, II2, and n are the highest HOMO's of the imidazolato ring.