105356-51-2 Usage
Description
4-(2-FURYL)-2,4-DIOXOBUTANOIC ACID is a cyclic chemical compound characterized by the presence of a furan ring and a dioxobutanoic acid group. It is recognized for its distinctive fruity and caramel-like odor, which makes it a valuable ingredient in the creation of artificial food flavors and fragrances. Additionally, its potential medicinal properties are being explored, particularly for the treatment of neurological and inflammatory conditions, highlighting its significance in both the food and pharmaceutical industries.
Uses
Used in Food Industry:
4-(2-FURYL)-2,4-DIOXOBUTANOIC ACID is used as a flavoring agent for its ability to impart a fruity and caramel-like aroma to various food products, enhancing their sensory appeal and consumer experience.
Used in Pharmaceutical Industry:
4-(2-FURYL)-2,4-DIOXOBUTANOIC ACID is used as a precursor in the synthesis of drugs, leveraging its unique chemical structure to contribute to the development of new medicinal compounds.
Used in Medicinal Research:
4-(2-FURYL)-2,4-DIOXOBUTANOIC ACID is being studied for its potential in treating neurological and inflammatory conditions, indicating its application as a research compound in the advancement of medical treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 105356-51-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,3,5 and 6 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 105356-51:
(8*1)+(7*0)+(6*5)+(5*3)+(4*5)+(3*6)+(2*5)+(1*1)=102
102 % 10 = 2
So 105356-51-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO2/c1-8-3-5-10(6-4-8)7-11-12(14)15-9(2)13-11/h3-7H,1-2H3/b11-7+
105356-51-2Relevant articles and documents
Discovery of α,γ-Diketo Acids as Potent Selective and Reversible Inhibitors of Hepatitis C Virus NS5b RNA-Dependent RNA Polymerase
Summa, Vincenzo,Petrocchi, Alessia,Pace, Paola,Matassa, Victor G.,De Francesco, Raffaele,Altamura, Sergio,Tomei, Licia,Koch, Uwe,Neuner, Philippe
, p. 14 - 17 (2007/10/03)
α,γ-Diketo acids (DKA) were discovered from screening as selective and reversible inhibitors of hepatitis C virus NS5b RNA-dependent RNA polymerase. The diketo acid moiety proved essential for activity, while substitution on the γ position was necessary for selectivity and potency. Optimization led to the identification of a DKA inhibitor of NS5b polymerase with IC50 = 45 nM, one of the most potent HCV NS5b polymerase inhibitors reported.
