1053626-47-3Relevant articles and documents
Opiate aromatic pharmacophore structure-activity relationships in CTAP analogues determined by topographical bias, two-dimensional NMR, and biological activity assays
Bonner, G. Gregg,Davis, Peg,Stropova, Dagmar,Edsall, Sidney,Yamamura, Henry I.,Porreca, Frank,Hruby, Victor J.
, p. 569 - 580 (2000)
Topographically constrained analogues of the highly μ-opioid-receptor- selective antagonist CTAP (H-D-Phe-c[Cys-Tyr-D-Trp-Arg-Thr-Pen]-Thr-NH2, 1) were prepared by solid-phase peptide synthesis. Replacement of the D-Phe residue with conformatio