105448-64-4

Upstream product

• 70871-22-6 (1S,2R,3R,5R)-2-hydroxymethyl-3-(tetrahydropyran-2-yl)oxy-7,7-ethylenedioxybicyclo<3.3.0>octane 
• 100-44-7 benzyl chloride 
• 110-87-2 3,4-dihydro-2H-pyran 
• 70870-94-9 (1S,2R,3R,5R)-2-ethoxycarbonyl-7,7-ethylenedioxy-3-hydroxy-bicyclo<3.3.0>octane 
• 105448-63-3 (1R,5S,6R,7R)-6-ethoxycarbonyl-3,3-ethylenedioxy-7-tetrahydropyranyloxybicyclo<3.3.0>octane 
• 70893-59-3 (1S,5R)-2-ethoxycarbonyl-7,7-ethylenedioxybicyclo<3.3.0>octan-3-one 

Downstream Products

• 73996-37-9 3α-hydroxy-7-oxo-2β-benzyloxymethylbicyclo<3.3.0>octane (α-isomer) 

Relevant academic research and scientific papers

A NEW SYNTHESIS OF (+)-6a-CARBAPROSTAGLANDIN I2 EMPLOYING YEAST REDUCTION OF A β-KETO ESTER DERIVED FROM cis-BICYCLOOCTANE-3,7-DIONE AS THE KEY-STEP

(+)-6a-carbaprostaglandin I2 (carbacyclin), a stable mimic of prostaglandin I2 (prostacyclin), was synthesized by utilizing the kinetic resolution of (+/-)-2-ethoxycarbonyl-7,7-ethylenedioxybicyclooctan-3-one in the course of its yeast reduction as