73996-37-9Relevant academic research and scientific papers
Facile synthesis of 6a-carbaprostaglandin I2
Konishi, Yoshitaka,Kawamura, Masanori,Iguchi, Yoichi,Arai, Yoshinobu,Hayashi, Masaki
, p. 4391 - 4399 (2015/01/08)
The optically active 6a-carbaprostaglandin I2 (2), a stable mimic of natural prostacyclin (1), was synthesized from the lactone 4 or the hydroxy acid 5, which were general synthetic intermediates for natural prostaglandins.
A NEW SYNTHESIS OF (+)-6a-CARBAPROSTAGLANDIN I2 EMPLOYING YEAST REDUCTION OF A β-KETO ESTER DERIVED FROM cis-BICYCLOOCTANE-3,7-DIONE AS THE KEY-STEP
Mori, Kenji,Tsuji, Masahiro
, p. 435 - 444 (2007/10/02)
(+)-6a-carbaprostaglandin I2 (carbacyclin), a stable mimic of prostaglandin I2 (prostacyclin), was synthesized by utilizing the kinetic resolution of (+/-)-2-ethoxycarbonyl-7,7-ethylenedioxybicyclooctan-3-one in the course of its yeast reduction as
PERHYDROPENTALENONE EQUIVALENT FROM COREY'S LACTONE
Mongelli, N.,Andreoni, A.,Zuliani, L.,Gandolfi, C.A.
, p. 3527 - 3530 (2007/10/02)
2-Oxa-bicyclooctane-3,7-diones work as a δ-oxo-β,γ-cyclopentenyl-acetic acid substrates when submitted to the Barco procedure in the synthesis of perhydropentalenones.
Facile synthesis of 6a-carbaprostaglandin I2
Konishi, Yoshitaka,Kawamura, Masanori,Iguchi, Yoichi,Arai, Yoshinobu,Hayashi, Masaki
, p. 4391 - 4399 (2014/12/10)
The optically active 6a-carbaprostaglandin I2 (2), a stable mimic of natural prostacyclin (1), was synthesized from the lactone 4 or the hydroxy acid 5, which were general synthetic intermediates for natural prostaglandins.
