1055-79-4 Usage
Description
1,3-bis(3,4,5-trimethoxyphenyl)urea is a urea derivative chemical compound with the molecular formula C22H26N2O8. It features two 3,4,5-trimethoxyphenyl groups attached to the urea core, which endows it with unique molecular structure and reactivity. 1,3-bis(3,4,5-trimethoxyphenyl)urea is frequently utilized in organic synthesis and medicinal chemistry due to its potential pharmaceutical applications and has been the subject of research for its biological activity and pharmacological properties.
Uses
Used in Organic Synthesis:
1,3-bis(3,4,5-trimethoxyphenyl)urea is used as a synthetic intermediate for the creation of various organic compounds. Its unique structure allows for versatile reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1,3-bis(3,4,5-trimethoxyphenyl)urea is used as a building block for the development of new drugs. Its specific molecular features are leveraged to design pharmaceuticals with targeted therapeutic effects.
Used in Pharmaceutical Development:
1,3-bis(3,4,5-trimethoxyphenyl)urea is employed as a potential candidate in the discovery and development of new therapeutic agents. Its biological activity and pharmacological properties are under investigation to determine its efficacy in treating various medical conditions.
Used in Biological Research:
1,3-bis(3,4,5-trimethoxyphenyl)urea is also utilized in biological research to study its interactions with biological systems. Understanding these interactions can provide insights into its potential applications in medicine and other related fields.
Used in Drug Discovery:
1,3-bis(3,4,5-trimethoxyphenyl)urea is used in drug discovery processes to identify new lead compounds. Its unique chemical properties make it a promising candidate for the development of innovative pharmaceuticals.
The specific applications of 1,3-bis(3,4,5-trimethoxyphenyl)urea may vary depending on the research or industrial context, but its versatility in chemical and biological settings highlights its importance in scientific and medical advancements.
Check Digit Verification of cas no
The CAS Registry Mumber 1055-79-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,5 and 5 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1055-79:
(6*1)+(5*0)+(4*5)+(3*5)+(2*7)+(1*9)=64
64 % 10 = 4
So 1055-79-4 is a valid CAS Registry Number.
1055-79-4Relevant articles and documents
Hydrosilane-Assisted Synthesis of Urea Derivatives from CO2and Amines
Zhao, Yulei,Guo, Xuqiang,Si, Zhiyao,Hu, Yanan,Sun, Ying,Liu, Yunlin,Ji, Zhongyin,You, Jinmao
, p. 13347 - 13353 (2020/11/02)
A methodology employing CO2, amines, and phenylsilane was discussed to access aryl- or alkyl-substituted urea derivatives. This procedure was characterized by adopting hydrosilane to promote the formation of ureas directly, without the need to prepare silylamines in advance. Control reactions suggested that FeCl3 was a favorable additive for the generation of ureas, and this 1,5,7-triazabicyclo[4.4.0]dec-5-ene-catalyzed reaction might proceed through nucleophilic addition, silicon migration, and the subsequent formal substitution of silylcarbamate.
Pd(OAc)2-catalyzed carbonylation of amines
Orito, Kazuhiko,Miyazawa, Mamoru,Nakamura, Takatoshi,Horibata, Akiyoshi,Ushito, Harumi,Nagasaki, Hideo,Yuguchi, Motoki,Yamashita, Satoshi,Yamazaki, Tetsuro,Tokuda, Masao
, p. 5951 - 5958 (2007/10/03)
A phosphine-free catalytic system [Pd(OAc)2-Cu(OAc) 2-air] induced a substrate-specific carbonylation of amines in boiling toluene under CO gas (1 atm). Symmetrical N,N′-dialkylureas were obtained by the carbonylation of primary amines. N,N,N′-Trialkylureas were selectively formed by addition of a secondary amine to the above reaction vessel. Secondary amines did not give tetraalkylureas. However, dialkylamines with a phenyl group on their alkyl chains, such as N-monoalkylated benzylic amine or phenethylamine derivatives, underwent a direct aromatic carbonylation to afford five- or six-membered benzolactams. In the carbonylation, the chelation effect or steric repulsion between Pd(II) and the meta-substituent in the ortho-palladation and the ring sizes of cyclopalladation products that were formed prior to carbonylation were found to generate good site selectivity and increase the reaction rate. In contrast, carbonylation of ω- arylalkylamines with a hydroxyl group gave neither ureas nor benzolactams but instead produced 1,3-oxazolidinones smoothly. Hydrochlorides of amines also underwent carbonylation to afford the corresponding amides under the conditions used. This procedure made it possible to prepare ureas of amino acid esters and N-alkylcarbamates in practical yields.
