105544-77-2

Upstream product

• 106-65-0 Dimethyl succinate 
• 2103-57-3 2,3,4-trimethoxybenzaldehyde 

Downstream Products

• 105544-78-3 4-(2,3,4-trimethoxyphenyl)-3-methoxycarbonyl butanoic acid 
• 105544-80-7 4-(2,3,4-trimethoxyphenyl)-4,5-dihydro-2(3H)-furanone 
• 105544-81-8 (3R*,4R*)-3-(2,3,4-trimethoxybenzyl)-4-(2,3,4-trimethoxybenzyl)-4,5-dihydro-2(3H)-furanone 

Relevant academic research and scientific papers

Studies on the Synthesis of highly substituted naphthol: Preparation of 6-Hydroxy-5,7-Dimethoxy-2-Naphthoic Acid, Isolated From Ulmus Thomasii

An improvement of a known procedure, affording substituted 4-hydroxy-2-naphthoic acid derivatives from aromatic aldehydes is described and its general applicability is shown through the preparation of a natural naphthalene derivative isolated from Ulmus thomasii.

Ruthenium dioxide in fluoro acid medium: I. A new agent in the biaryl oxidative coupling. Application to the synthesis of non phenolic bisbenzocyclooctadiene lignan lactones

Ruthenium (IV) dioxide dihydrate in fluoro acid medium was found to be a very efficient agent for the oxidative coupling of non phenolic lignans and their derivatives, and this method was applied to the total synthesis of (+/-)-neoisostegane 2a and (+/-)-steganolide A 2b. This procedure was also used to obtain the first stereospecific synthesis of a cis-bisbenzocyclooctadiene lactone, the (+/-)-deoxyschizandrin 17, of which, was afforded by a short reduction sequence.