105544-78-3

Upstream product

• 2103-57-3 2,3,4-trimethoxybenzaldehyde 
• 106-65-0 Dimethyl succinate 
• 105544-77-2 3-(methoxycarbonyl)-4-(2,3,4-trimethoxyphenyl)-3-butenoic acid 

Downstream Products

• 105544-80-7 4-(2,3,4-trimethoxyphenyl)-4,5-dihydro-2(3H)-furanone 
• 105544-81-8 (3R*,4R*)-3-(2,3,4-trimethoxybenzyl)-4-(2,3,4-trimethoxybenzyl)-4,5-dihydro-2(3H)-furanone 

Relevant academic research and scientific papers

Ruthenium dioxide in fluoro acid medium: I. A new agent in the biaryl oxidative coupling. Application to the synthesis of non phenolic bisbenzocyclooctadiene lignan lactones

Ruthenium (IV) dioxide dihydrate in fluoro acid medium was found to be a very efficient agent for the oxidative coupling of non phenolic lignans and their derivatives, and this method was applied to the total synthesis of (+/-)-neoisostegane 2a and (+/-)-steganolide A 2b. This procedure was also used to obtain the first stereospecific synthesis of a cis-bisbenzocyclooctadiene lactone, the (+/-)-deoxyschizandrin 17, of which, was afforded by a short reduction sequence.

LE TETRAKIS(TRIFLUOROACETATE) DE RUTHENIUM(IV), NOUVEAU CATALYSEUR A TEMPERATURE AMBIANTE DU COUPLAGE BIARYLIQUE OXIDANT NON PHENOLIQUE-PREMIERE SYNTHESE TOTALE BIOMIMETIQUE DU NEOISOSTEGANE-

In situ generated Ruthenium(IV) tetrakis(trifluoroacetate) -a new organometallic reagent- was used in intramolecular non-phenolic oxydative biaryl coupling of dibenzylbutanolides, and an application to the first total synthesis of neoisostegane was perfor