105544-80-7Relevant academic research and scientific papers
ISOLEMENT, ETUDE STEREOCHIMIQUE ET SYNTHESE BIOMIMETIQUE DU STEGANOLIDE A, NOUVEAU LIGNANE BISBENZOCYCLOOCTADIENOLACTONIQUE DE STEGANOTAENIA ARALIACEA
Taafrout, M.,Landais, Y.,Robin, J.-P.,Davoust, D.
, p. 1781 - 1784 (1986)
Isolation of steganolide A from Steganotaenia araliacea (Apiaceae) - a new original bisbenzocyclooctadiene lignan lactone bearing an "iso" = M-6R biaryl junction (P,M, = Plus, Minus in terms of helicity nomenclature applied to axial chirality) - and short biomimetic total synthesis using intramolecular nonphenolic oxydative biaryl coupling as a key reaction were performed.
Ruthenium dioxide in fluoro acid medium: I. A new agent in the biaryl oxidative coupling. Application to the synthesis of non phenolic bisbenzocyclooctadiene lignan lactones
Landais,Robin,Lebrun
, p. 3787 - 3804 (2007/10/02)
Ruthenium (IV) dioxide dihydrate in fluoro acid medium was found to be a very efficient agent for the oxidative coupling of non phenolic lignans and their derivatives, and this method was applied to the total synthesis of (+/-)-neoisostegane 2a and (+/-)-steganolide A 2b. This procedure was also used to obtain the first stereospecific synthesis of a cis-bisbenzocyclooctadiene lactone, the (+/-)-deoxyschizandrin 17, of which, was afforded by a short reduction sequence.
LE TETRAKIS(TRIFLUOROACETATE) DE RUTHENIUM(IV), NOUVEAU CATALYSEUR A TEMPERATURE AMBIANTE DU COUPLAGE BIARYLIQUE OXIDANT NON PHENOLIQUE-PREMIERE SYNTHESE TOTALE BIOMIMETIQUE DU NEOISOSTEGANE-
Landais, Y.,Robin, J.-P.
, p. 1785 - 1788 (2007/10/02)
In situ generated Ruthenium(IV) tetrakis(trifluoroacetate) -a new organometallic reagent- was used in intramolecular non-phenolic oxydative biaryl coupling of dibenzylbutanolides, and an application to the first total synthesis of neoisostegane was perfor
