105590-88-3Relevant academic research and scientific papers
Cephalosporin prodrugs of paclitaxel for immunologically specific activation by L-49-sFv-β-lactamase fusion protein
Vrudhula, Vivekananda M.,Kerr, David E.,Siemers, Nathan O.,Dubowchik, Gene M.,Senter, Peter D.
, p. 539 - 542 (2003)
Paclitaxel conjugates of 7-phenylacetamidocephalosporanic acid were prepared as prodrugs for site specific activation by targeted β-lactamase. Immunologically specific activation of the prodrug 5 containing 3,3-dimethyl-4-amino-butyric acid as linker in combination with the fusion protein L-49-sFv-β-lactamase was demonstrated in vitro on 3677 melanoma cells.
THE CHEMISTRY OF PEPTIDES RELATED TO METABOLITES OF TRICHODERMA SPP. 2. AN IMPROVED METHOD OF CHARACTERIZATION OF PEPTIDES OF 2-METHYLALANINE
Shaw, I. M.,Taylor, A.
, p. 164 - 173 (2007/10/02)
4-Chlorobenzoylazide reacts with amino acid and peptide esters to give the 4-chlorobenzoyl derivatives in 60-90percent yield, at room temperature, without measurable racemization.The reaction also proceeds smoothly with hindered amines such as methyl 2-me
