105729-06-4

Basic information

• Product Name: 2-METHOXY-1-PYRIDIN-2-YLETHANONE
• Synonyms: 2-METHOXY-1-PYRIDIN-2-YLETHANONE;2-methoxy-1-pyridin-2-ylethanone(SALTDATA: FREE)
• CAS NO: 105729-06-4
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151.16
• Mol File: 105729-06-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 242.6°C at 760 mmHg
• Flash Point: 100.5°C
• Appearance: /
• Density: 1.102g/cm³
• Vapor Pressure: 0.0337mmHg at 25°C
• Refractive Index: 1.506
• CAS DataBase Reference: 2-METHOXY-1-PYRIDIN-2-YLETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXY-1-PYRIDIN-2-YLETHANONE(105729-06-4)
• EPA Substance Registry System: 2-METHOXY-1-PYRIDIN-2-YLETHANONE(105729-06-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 105729-06-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H9NO2/c1-11-6-8(10)7-4-2-3-5-9-7/h2-5H,6H2,1H3

Upstream product

• 67-56-1 methanol 
• 87221-66-7 trimethyl-(1-pyridinylvinyloxy)-silane 

Relevant articles and documents

Metal-Metal Exchange of α-Metallo Ketones. Novel Formation of α-Acyl Anion and α-Keto Carbonium Ion Equivalents from (Aryl)phenacyl TlIII, PbIV, and HgII Systems

The novel class of α-metallo ketones RCOCH2TlIIItolyl(OCOCF3) where R = phenyl, substituted phenyl, thienyl, pyridinyl, and tert-butyl have been synthesized and characterized by 1H NMR and 13C NMR.These compounds serve as anion equivalents in the TiCl4-mediated aldol condensation.Metal-metal exchange with iodosylbenzene or lead tetraacetate leads to α-nucleophilic substitution derived from the formal α-keto carbonium ion equivalent.The corresponding p-CH3OC6H4COCH2PbIVC6H4OCH3-p-(OCOCH3)2 and (p-CH3OC6H4COCH2)2HgII analogues were synthesized and shown to likewise behave as either enolate anion or α-keto carbonium ion equivalents upon metal-metal exchange with TiIV, PbIV, or IIII.The importance of this work is that the range of reactivity of α-metallo ketones may be selectively adjusted by metal-metal or metal-metalloid exchange.