1058092-82-2Relevant academic research and scientific papers
Rates of the oxidative addition of benzyl halides to a metallacyclic palladium(II) complex and of the reductive elimination from a benzyl-palladium(IV) complex
Amatore, Christian,Catellani, Marta,Deledda, Sara,Jutand, Anny,Motti, Elena
, p. 4549 - 4554 (2008)
Pd(II) metallacyclic complexes are key intermediates in sequential reactions in which three new C-C bonds are formed in an aromatic ring. The Pd(II) metallacyclic complex 10 with phenanthroline as ligand undergoes oxidative addition to benzyl bromide or chloride in DMF to generate benzyl-Pd(IV) complexes. The rate constant of the oxidative addition is determined by means of electrochemical techniques, with the expected reactivity order PhCH2Br (k1Br = 3.6 M-1 s-1) > PhCH2Cl (k1Cl = 6 × 10-3 M -1 s-1) at 29°C. When the benzyl-Pd(IV) complex is generated from PhCH2Br, the oxidative addition is followed by a slow C-C reductive elimination, which gives a Pd(II) complex. The rate constant of the reductive elimination has been determined in DMF (k2Br = 6 × 10-4 s-1) at 29°C.
