1058138-76-3Relevant academic research and scientific papers
Convenient synthesis of pyrrolidines by amphiphilic allylation of imines with 2-methylenepropane-1,3-diols
Kimura, Masanari,Tamaki, Takato,Nakata, Masanori,Tohyama, Katsumi,Tamaru, Yoshinao
supporting information; experimental part, p. 5803 - 5805 (2009/03/11)
(Chemical Equation Presented). A straightforward route: The combination of a palladium catalyst and triethylborane promotes the amphiphilic (nucleophilic-electrophilic) allylation of aldimines, prepared in situ from a wide variety of aromatic and aliphatic aldehydes and amines, with commercially available 2-methylenepropane-1,3-diols to provide pyrrolidines (see scheme).
