56030-48-9Relevant academic research and scientific papers
Convenient synthesis of pyrrolidines by amphiphilic allylation of imines with 2-methylenepropane-1,3-diols
Kimura, Masanari,Tamaki, Takato,Nakata, Masanori,Tohyama, Katsumi,Tamaru, Yoshinao
supporting information; experimental part, p. 5803 - 5805 (2009/03/11)
(Chemical Equation Presented). A straightforward route: The combination of a palladium catalyst and triethylborane promotes the amphiphilic (nucleophilic-electrophilic) allylation of aldimines, prepared in situ from a wide variety of aromatic and aliphatic aldehydes and amines, with commercially available 2-methylenepropane-1,3-diols to provide pyrrolidines (see scheme).
Diastereoselective epoxidation of allylic diols derived from Baylis-Hillman adducts
Porto, Ricardo S.,Vasconcellos, Mario L. A. A.,Ventura, Elizete,Coelho, Fernando
, p. 2297 - 2306 (2007/10/03)
The results of a highly diastereoselective epoxidation of allylic diols derived from Baylis-Hillman adducts are reported. The formation of an intramolecular hydrogen bond seems to be responsible for the high anti diastereoselection obtained in this epoxid
An improved procedure for the preparation of the O,2-dianion of allyl alcohol
Hegde, Sayee G.,Myles, David C.
, p. 2111 - 2115 (2007/10/03)
An improved procedure for the preparation of the O,2-dianion of allyl alcohol is described. The use of the magnesium alkoxide of 2-bromopropen-1- ol instead of the known lithium salt, suppresses dehydrohalogenation upon treatment with tert-butyl lithium a
A Facile Preparation of Alkenyl- and Allenylmetallic Compounds by Means of Iodine-Metal Exchange and Their Use in Organic Synthesis
Shinokubo, Hiroshi,Miki, Hiroaki,Yokoo, Toshiaki,Oshima, Koichiro,Utimoto, Kiitiro
, p. 11681 - 11692 (2007/10/02)
Stereospecific lithium-halogen exchange of alkenyl iodides was performed upon treatment with butyllithium in non-polar solvents such as hexane, benzene, and toluene at 25 deg C to provide alkenylllithiums quantitatively with retention of the configuration.Metal-iodine ecxhange of allenyl iodides with n-BuLi, i-PrMgBr or Et2Zn was also performed effectively to afford the corresponding allenylmetallic reagents.An addition of carbonyl compounds to the metallic reagents gave homopropargylic alcohols with high regioselectivity in good yields.
