105850-77-9

Upstream product

• 6338-41-6 5-hydroxymethyl-furan-2-carboxylic acid 
• 1623-88-7 5-chloromethylfurfural 

Downstream Products

• 2528-00-9 5-Chloromethyl-furan-2-carboxylic acid ethyl ester 
• 2144-37-8 methyl 5-(chloromethyl)-2-furoate 
• 14946-15-7 4,6-Bis-methyl-mercapto-2-<5-chlormethylfuryl-(2)>-1,3,5-triazin 

Relevant academic research and scientific papers

Diversification of the Renewable Furanic Platform via 5-(Chloromethyl)furfural-Based Carbon Nucleophiles

Biobased 5-(chloromethyl)furoate and 5-methylfuroate esters can be deprotonated to function as furylogous lithium enolates, and the former can also undergo zinc insertion to access Reformatsky-type chemistry. Carbon nucleophilicity represents hitherto lit

COMPOUND AND DETERGENT COMPOSITION

A furan-based surfactant comprising a beta sulphonate head group, a furan and a C10-20 hydrophobic group which is either attached directly to the furan or by way of a linker. A laundry composition or a hand dish wash cleaning composition comprising said s

PREPARATION OF ACID CHLORIDES FROM 5-(CHLOROMETHYL) FURFURAL

Acid chloride derivatives of 5-(chloromethyl)furan-2-carboxylic acid and furan-2,5-dicarboxylic acid (FDCA) can be produced in high yield by treatment of the precursor aldehydes 5-(chloromethyl)furfural (CMF) and 2,5-diformylfuran (DFF) with tert-butyl hypochlorite, which is inexpensively prepared from commercial bleach and tert-butanol. 5-(Chloromethyl)furan-2-carbonyl chloride (CMFCC) and furan-2,5-dicarbonyl chloride (FDCC) are highly useful intermediates for the production of furoate ester biofuels and polymers of FDCA.

Production of 5-(chloromethyl)furan-2-carbonyl chloride and furan-2,5-dicarbonyl chloride from biomass-derived 5-(chloromethyl)furfural (CMF)

Acid chloride derivatives of 5-(chloromethyl)furan-2-carboxylic acid and furan-2,5-dicarboxylic acid (FDCA) can be produced in high yield by treatment of the precursor aldehydes 5-(chloromethyl) furfural (CMF) and 2,5-diformylfuran (DFF) with tert-butyl hypochlorite, which is inexpensively prepared from commercial bleach and tert-butanol. 5-(Chloromethyl)furan-2-carbonyl chloride (CMFCC) and furan-2,5-dicarbonyl chloride (FDCC) are highly useful intermediates for the production of furoate ester biofuels and polymers of FDCA.

COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER STEM CELLS

The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof: Formula (I).

FURAN DERIVATIVES FOR PREVENTING AND CURING OSTEOPOROSIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

The present invention relates to furan derivatives and pharmaceutical compositions containing them to prevent and cure osteoporosis. The furan derivatives of the present invention have effect on bone proliferation with the side effect reduced, so that they can be used for bone disease.

FURAN DERIVATIVES FOR PREVENTING AND CURING OSTEOPOROSIS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

The present invention relates to furan derivatives and pharmaceutical compositions containing them to prevent and cure osteoporosis. The furan derivatives of the present invention have effect on bone proliferation with the side effect reduced, so that they can be used for bone disease.

Synthesis of isomeric phosphonomethylated N,N-diethylfurancarboxamides

A new method for preparing chloromethyl derivatives of N,N-dialkylfurancarboxamides was developed and all six possible isomers were obtained. These compounds are phosphorylated under the Michaelis-Becker reaction conditions to give the corresponding phosphonates. The conditions of phosphorylation of the isomeric furancarboxamides are similar and, in spite of the presence of an electron-acceptor substituent in the furan ring, more rigid conditions than in the case of chloromethylated alkylfurans. A plausible explanation of the observed effect is proposed.

Design, synthesis, and biological activity of prazosin-related antagonists. Role of the piperazine and furan units of prazosin on the selectivity for α1-adrenoreceptor subtypes

Prazosin-related quinazolines 4-20 were synthesized, and their biological profiles at α1-adrenoreceptor subtypes were assessed by functional experiments in isolated rat vas deferens (α(1A)), spleen (α(1B)), and aorta (α(1D)) and by binding assa