105875-09-0Relevant articles and documents
A Cross Metathesis Based Protocol for the Effective Synthesis of Functionalised Allyl Bromides and Chlorides
Bandini, Marco,Cozzi, Pier Giorgio,Licciulli, Sebastiano,Umani-Ronchi, Achille
, p. 409 - 414 (2004)
Functionalised allyl halides, useful starting materials for the preparation of substituted organometallic reagents can be simply obtained by a straightforward approach. Hoveyda's ruthenium carbene catalyst 3, used in catalytic amount (2 mol%), is able to
Visible-light-mediated conversion of alcohols to halides
Dai, Chunhui,Narayanam, Jagan M.R.,Stephenson, Corey R.J.
experimental part, p. 140 - 145 (2012/02/06)
The development of new means of activating molecules and bonds for chemical reactions is a fundamental objective for chemists. In this regard, visible-light photoredox catalysis has emerged as a powerful technique for chemoselective activation of chemical bonds under mild reaction conditions. Here, we report a visible-light-mediated photocatalytic alcohol activation, which we use to convert alcohols to the corresponding bromides and iodides in good yields, with exceptional functional group tolerance. In this fundamentally useful reaction, the design and operation of the process is simple, the reaction is highly efficient, and the formation of stoichiometric waste products is minimized.
N-heterocyclic carbene-catalyzed hydroacylation of unactivated double bonds
Hirano, Keiichi,Biju, Akkattu T.,Piel, Isabel,Glorius, Frank
supporting information; experimental part, p. 14190 - 14191 (2010/02/15)
(Chemical Equation Presented) An intramolecular N-heterocyclic carbene (NHC)-catalyzed hydroacylation of unactivated double bonds is reported. Systematic variation of the catalyst structure revealed an N- mesitylthiazolylidene annulated with a seven-membered ring to be especially reactive. This NHC enables a unique C-C bond-forming reaction to afford substituted chroman-4-ones in moderate to excellent yields, even ones containing all-carbon quaternary centers.
Catalytic Iron-Mediated Triene Carbocyclizations: Stereoselective Five-Membered Ring Forming Carbocyclizations
Takacs, James M.,Myoung, Young-Chan,Anderson, Lawrence G.
, p. 6928 - 6942 (2007/10/02)
The full details of investigations into the regiochemistry and stereochemistry of iron-catalyzed carbocyclizations of 2,7,9-decatriene derivatives to form five-membered carbocyclic ring systems are described.The roles of the allylic substituent, the alkene geometry, diene substitution, and the influence of resident stereogenic centers incorporated in the tether chain connecting the reacting 1,3-diene and alkene subunits are discussed.
SYNTHESIS OF 3-DESMETHYLHEXAPRENOL WT3C2OH
Grigor'eva, N. A.,Yudina, O. N.,Cherepanova, E. G.,Moiseenkov, A. M.
, p. 712 - 715 (2007/10/02)
A six-step synthesis of 3-desmethylhexaprenol WT3C2OH was carried out in continuation of studies of the relationship between the structure of polyprenols and their biological properties.
SYNTHETIC APPROACH TOWARD MITOMYCINS. SYNTHESIS OF 9-BENZYLOXYMETHYL-5-METHOXY-4-METHYL-3H-PYRROLOINDOL-4,5-DIONE
Naruta, Yoshinori,Nagai, Naoshi,Maruyama, Kazuhiro
, p. 1383 - 1386 (2007/10/02)
2-Azido-3-(1'-benzyloxymethyl-2',4'-pentadienyl)-5-methoxy-6-methyl-1,4-benzoquinone is prepared and its thermal decomposition under the presence of Cu(acac)2 affords the corresponding 3H-pyrroloindol-5,8-dione, which is the important precursor for
